Discovery Pharmaceutics Scientist Jobs

Knowledge of in vivo pharmacology principles, drug metabolism and in vivo dosing and sampling skills

Demonstrated understanding and experience in performing pharmacological and mechanistic studies in in-vivo models of Retinal Diseases, including all pertinent ex-vivo analyses.

Expertise with integrated physiological assessments in the eye, including ocular dosing and dissection techniques. Experience in ocular imaging is a plus

Demonstrates good oral, written, and interpersonal skills and is a strong collaborator and team player.

Protocol development and approval in partnership with IVS and IACUC. Responsible for validity, reproducibility, interpretation, documentation.

Works under limited supervision with a high level of autonomy.

Hands-on laboratory experience in carrying out on-DNA synthesis and methodology development.

Experience analyzing and purifying DNA-conjugates using common analytical tools (LCMS/HPLC).

Experience working in the drug discovery field – drug design, synthesis, and SAR based hit-to-lead optimization.

Postdoctoral or industrial work experience in the DEL field.

Experience working in the PROTAC-based drug discovery programs.

Experience working with high-throughput analytical and purification systems relevant to DEL-applications.

Excellent organization, communication, time management, writing and creative problem-solving skills are essential.

Liaise between our office and the Grand Jury, Clerks Office, and Court Clerks.

5 years of experience in an area related to the duties as described above.

Literacy in computer applications, Microsoft Suite; Excel required; knowledge of SQL, CIS, and other City oriented systems.

Responsibilities Include But Are Not Limited To

Assist with the entire e-Discovery process, from ingestion, production of e-Discovery materials, and through archiving.

Must have strong communication and presentation skills.

Work closely with the Photography Department to develop ideas, manage and maintain the network brand.

Work closely with the Production Manager of Digital/Print Design to keep all projects on time and on budget

Organize and manage the media files graphics assets and graphics deliverables files on the various servers and archive systems

At least 3+ years of graphic design experience, preferably within a TV network or design studio

Expert knowledge of all current graphic software including Adobe CC Suite, as well as Microsoft PowerPoint

Knowledge of data structure, capture, analysis and visualization is desired; experience with Spotfire or Tableau would be beneficial.

Excellent organizational and interpersonal skills.

Excellent written and verbal communication skills.

Skills with working in research teams at interfaces and in multi-disciplinary environments is beneficial.

Non-standard Work Schedule, Travel Or Environment Requirements

Closely collaborate with Research partners to evaluate molecular attributes relevant to drug delivery and influence team strategies.

Experience in automation and screening a plus.

Manage cryopreservation of tissues and cell lines.

4+ years of academic and / or industry experience

2+ years of academic and / or industry experience

3D Model Systems experience with matrix-attached models, spheroids and/or organoids

Extensive in vitro cell culture experience including establishing new cells lines with CRISPR, lenti-virus, shRNA, and inducible expression systems.

Experience and working knowledge of concepts including but not limited to in vitro pharmacology, cell biology, molecular biology, histology/immunohistochemistry, FACS, etc.

Master’s degree with 6 years of relevant industry experience

Excellent communication skills with the proven ability to build collaborative relationships and work effectively as a member of a multidisciplinary team

Continuously develops more in-depth knowledge of UCB's drug discovery process through reading, conferences and seminars

Experience with culturing a broad variety of mammalian cells; proficiency with maintenance and differentiation of iPSCs is preferred

Experience training junior researchers is a plus (CoOps, Interns)

Experience with advanced in vitro model systems including organoids and other 3D culture systems is highly preferred

Experience with RNAi is preferred

Strong oral and written communication skills and a demonstrated ability to contribute effectively to group projects in a team-oriented environment

SiRNA drug candidate screening, hit identification, and lead optimization

Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays; PCR

In vivo drug candidate testing (e.g. mouse dosing; sample analysis)

Position will be hired based on knowledge and/or level of experience.

Exhibit a can-do attitude with excellent interpersonal and communication skills to multiple teams across different functional areas

Knowledge of molecular biology and/or immunology concepts

Experience with aseptic mammalian cell culture technique

Experience in immunoassays using techniques like flow cytometry, ELISA, homogeneous assays and microscopy

Strong attention to quality and details when exercising organizational, documentation and communication skills

Excellent communication, organizational, and time management skills

Support the set-up, operation, and maintenance of our automated cell line management system

Additional Preferred Qualifications And Experience

Bachelor’s Degree, 2+ years of academic and / or industry experience

Requires a good understanding and practical experience in routine mammalian cell culture and microscopy

Experience with molecular biology techniques such as western blotting, immunostaining, DNA & RNA extractions, and qPCR

• Helping with various lab management needs

• Strong knowledge and hands on experience with molecular biology techniques

Responsibilities include, but are not limited to the following:

• Broad experience with mammalian cell culture (cell lines and primary cells)

• Excellent verbal and written communication skills

• Cell culture work, transfections with nucleic acids, flow cytometry

6 months of hands-on experience building and maintaining annotated imaging dataset(s)

1 year of hands-on experience building & modifying PyTorch vision models

2 years of experience programming in Python

6 months of experience building JavaScript applications to interact with analytical results

Strong coding skills in Python and MATLAB, or R

Experience with developing algorithms and deploying software in machine learning techniques

Identify, plan, and execute well defined scientific projects and communicates program strategy and timelines to management.

Knowledge in immunology or immune oncology. Understanding of cell and gene therapies.

Experience with biologics is prefered (Antibodies, ADCs, Cell therapeis etc)

Experience in molecular biology and biochemical techniques such as western blot, molecular cloning is a plus.

What Takeda Can Offer You

and Long-Term Incentive benefits. Employees are eligible to participate in

Inspire team members, provide feedback to group members and management team

Advanced knowledge of mucosal biology, lung diseases, cell/stem cell platforms

Lab experience includes many of the techniques and tools listed above

An experienced mentor who successfully fosters confidence and team commitment

2+ years of relevant postdoctoral employment experience

Preferred: 1-5 years of industry experience

Manage several projects simultaneously and act as point of accountability for in vitro display efforts on projects.

Initiate and manage external academic collaborations in the antibody discovery and engineering space.

Effectively manage projects and resources to maximize progress.

Hands-on experience with antibody phage/yeast display, HT screening, flow cytometry and kinetic analysis is required.

Experience with library construction, NGS/deep mining, multi-specific modalities, alternative antibody scaffolds and engineering is highly preferred.

Highly analytical mind, attention to detail, and organizational skills are critical.

Leverage and expand automated capabilities to perform suitable components of daily workflows.

Exhibit a can-do attitude with excellent interpersonal and communication skills to multiple teams across different functional areas

BS or MS in Biology or other closely related field with typically 0-3+ years of industry or academic experience

Knowledge of basic immunology concepts

Strong attention to quality and details when exercising organizational, documentation and interpersonal skills

Experience with mammalian cell culture, aseptic technique is highly desired

Create databases and respond to the needs of department management, legal teams, or clients.

Manage the implementation of database systems, external web-based document repositories, external web-based case management tools, etc.

Manipulate data load files between litigation review platforms to assure quality and cost efficiency of document review projects and document management.

Client interaction and support including project management, budgeting, status reporting, etc.

Relevant experience required, as well as experience in a Litigation Technology Support role; Full-cycle litigation experience required.

Technical knowledge to include Microsoft O365; Relativity; and SQL

Minimum Qualification (education, experience and/or training, required certifications):

·Knowledge and hands-on experience on microbiome research and NGS that include microbiome sample collection/inventory and microbiome profiling.

·Knowledge on basic bioinformatic skills (i.e. SQL, phyton/perl programming, genome assembly/annotation, microbiome analysis).

·Working experience with automation systems (e.g. liquid handler, automated DNA extraction platforms)

·Excellent oral and written communication skills

·Capability to manage multiple tasks and projects

2+ years product management experience in a consumer products company

Pilot new ways for users to interact with Tesla, always keeping customer experience top of mind

Experience with agile software development

Excellent written and verbal communication skills

Family-building, fertility, adoption and surrogacy benefits

401(k) with employer match, Employee Stock Purchase Plans, and other financial benefits