Associate Scientist, Ipsc Technologies Discovery Biology Neuroscience

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Neuroscience TRC is committed to development of transformational therapeutics for patients with neurodegenerative and neuromuscular diseases. We have built a network of external partnerships across multiple treatment modalities (small molecules, biologics and RNA targeting) that leverage our leadership in protein homeostasis and inflammation to attach neurological diseases. Internal research focuses on protein homeostasis by direct and ligand directed degradation, neuroinflammation and remyelination.

Areas of interest include, but are not limited to, the following approaches

Disease modifying therapies for neurodegenerative, neuro-inflammatory and neuromuscular diseases; CNS targets that modulate protein homeostasis, protein clearance, inflammation and reduce or eliminate toxic protein production; Emerging technologies (RNA, DNA targeting, gene regulation, editing and replacement, vector optimization) that when matched to underlying disease genetics can deliver a precision medicine portfolio with a high probability of success to address unmet medical needs; Targets in orphan/rare neurological and neuromuscular diseases. AI/ML in target identification and neurology drug discovery; Translational tools and technologies such as digital neuroimaging and fluid biomarkers to track neurodegenerative diseases; Novel blood brain-barrier delivery technologies.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Position Responsibilities

In the role as an Associate Scientist within the Neuroscience Discovery Biology TRC, the ideal candidate will

• Participate directly in validation of new targets for neurodegenerative diseases and developing disease relevant assays
• Collaborate with the Automation Engineer to onboard, validate and maintain iPSC workflows on our automation platform. Report bugs and propose new features for the platform
• Perform iPSC maintenance and differentiation to specialized neurons for target validation and drug discovery efforts
• Support cell engineering efforts including cell line development, quality control, expansion, and characterization of edited cell lines
• Support the set-up, operation, and maintenance of our automated cell line management system
• Participate in troubleshooting of routine experiments
• Organize and maintain experimental data in lab notebook

Experience =

Basic Qualifications

• Bachelor’s Degree, 2+ years of academic and / or industry experience

Preferred Qualifications

• Ability to work effectively with others in a collaborative team environment
• Fast learner who can independently conduct experiments following established protocols and can develop new techniques
• Excellent communication, organizational, and time management skills
• Requires a good understanding and practical experience in routine mammalian cell culture and microscopy
• Experience with molecular biology techniques such as western blotting, immunostaining, DNA & RNA extractions, and qPCR
• Works under minimal supervision for routine activities and moderate supervision for non-routine activities

Additional Preferred Qualifications And Experience

• Experience with automation equipment such a liquid handlers, imagers, plate readers
• Experience with iPSC differentiation to a variety of specialized neurons and characterization of iPSC-neurons
• Experience with high throughput cell biology including high content imaging and signal transduction assays
• Experience with genome editing, CRISPR engineering, RNAi approaches.
• Significant cell culture experience with cell lines, primary cells and iPSCs
• Ability to learn and become independent enough to drive iPSC workflows with minimal supervision

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BMSNEURO

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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