Associate Scientist Ii Or Scientist I, In Vivo Antibody Discovery

The Biotherapeutics and Genetics Medicine department within Discovery Research is seeking a highly motivated research scientist to join the in vivo antibody discovery team at AbbVie Bioresearch Center (ABC). The ABC site, based in Worcester, MA, offers the unique setting where Biologics drug discovery, development and manufacturing coexist in one location. Our team interacts with multidisciplinary groups across AbbVie focused on developing therapies for Immunology, Neurology and Oncology diseases. We utilize innovative immunization approaches, advanced multiplex screening assays and best-in-class automation platforms to enable successful antibody discovery against complex targets.
As an integral part of the group, the ideal candidate will:

• Exhibit a can-do attitude with excellent interpersonal and communication skills to multiple teams across different functional areas
• Exercise proficiencies in mammalian tissue culture, molecular techniques, and binding assays such as ELISA and flow cytometry
• Execute all phases of in vivo antibody discovery campaigns by hybridoma generation or single B cell discovery isolation including screening, cell culture and antibody characterization
• Analyze and document results, placing data in proper scientific context through review of relevant literature and report findings at team meetings
• Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment

Qualifications:

• BS or MS in Biology or other related field with 3-5+ years (BS), or 0-2+ years (MS) of industry or academic experience
• Experience in immunoassays using techniques like flow cytometry, ELISA, homogeneous assays and microscopy
• Proven flexibility to deal with changing timelines and shifting work priorities
• Competency with software programs, including MS Excel, PowerPoint, Word
• Experience with aseptic mammalian cell culture technique
• Strong attention to quality and details when exercising organizational, documentation and communication skills
• Knowledge of molecular biology and/or immunology concepts
• Position will be hired based on knowledge and/or level of experience.

Desirable:

• Molecular biology techniques including molecular cloning
• Experience with microfluidics and single cell analysis
• Experience with advanced automation platforms and programming

Position will be filled at level commensurate with extent of education, experience, and accomplishment
AbbVie is an equal opportunity employer including disability/vets. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a disabled veteran, recently separated veteran, Armed Forces service medal veteran or active duty wartime or campaign badge veteran or a person’s relationship or association with a protected veteran, including spouses and other family members, or any other protected group status. We will take affirmative action to employ and advance in employment qualified minorities, women, individuals with a disability, disabled veterans, recently separated veterans, Armed Forces service medal veterans or active-duty wartime or campaign badge veterans. The Affirmative Action Plan is available for viewing in the Human Resources office during regular business hours.