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Scientist Discovery Protein Sciences Jobs in San Francisco, San Mateo, California

Scientist I, Dna Encoded Library Technology – Discovery Chemistry
By Nurix Therapeutics At San Francisco Bay Area, United States
Hands-on laboratory experience in carrying out on-DNA synthesis and methodology development.
Experience analyzing and purifying DNA-conjugates using common analytical tools (LCMS/HPLC).
Experience working in the drug discovery field – drug design, synthesis, and SAR based hit-to-lead optimization.
Postdoctoral or industrial work experience in the DEL field.
Experience working in the PROTAC-based drug discovery programs.
Experience working with high-throughput analytical and purification systems relevant to DEL-applications.
Research Scientist, Protein Science
By Septerna At South San Francisco, CA, United States
Effectively analyze and interpret data, as well as communicate updates to management and cross-functional teams
Minimum of 4+ years of research experience, 0-2 years of related experience post-PhD
Proven expertise in protein purification techniques, with working knowledge of FPLC platforms (AKTA, Bio-Rad).
Experience with prokaryotic and eukaryotic expression vectors and construct design for structural biology studies.
Attention to detail, accurate record keeping, and strong oral and written communication skills
Prior experience with protein purification and protein characterization of membrane-spanning proteins such as GPCRs, is a bonus.
Scientist - Protein Display Technologies
By BioSpace At Redwood City, CA, United States
Bachelor's Degree in Biochemistry, Bioengineering, Molecular Biology, or related fields and 5+ years of academic / industry experience
OR Master's Degree in Biochemistry, Bioengineering, Molecular Biology, or related fields and 3+ years of academic / industry experience
OR PhD No experience required
Experience and enthusiasm to work with mRNA and yeast display
In-depth understanding and experience in antibody engineering is highly desirable
Demonstrated experience in working in a cross-functional organization is required
Research Associate - Protein Sciences
By Parvus Therapeutics Inc At South San Francisco, CA, United States
Manage and maintain mammalian suspension and adherent cell lines and perform aseptic techniques as needed
One to two years relevant experience in an academic lab (classes not included) or biotechnology work experience is required
Organized and detail oriented, possessing excellent record-keeping skills
Experience with protein purification using AKTA FPLC system is preferred
Experience with aseptic technique and mammalian cell culture is preferred
Learn and perform protein purification using various chromatography techniques and run conjugation reactions
Pkdm - Scientist (Cellular & Protein Interaction Group)
By Amgen At , South San Francisco, Ca $136,183 - $171,658 a year
Flexible work models, including remote work arrangements, where possible
Master’s degree with 4 years of experience in pharma/biopharma or
Bachelor’s degree with 6 years of experience in pharma/biopharm
Leverage in vitro cellular assay tools to establish in vitro-in vivo correlations (IVIVCs) of early-stage multi-specific therapeutic proteins and engineered monotherapies
Design biological and/or biophysical experiments in support of both drug discovery and early development programs, and operating within a modality-independent framework.
Emphasize technology development that can be enabling of in vitro PKDM assessments
Scientist - Translational Sciences
By BioSpace At South San Francisco, CA, United States
PhD (or equivalent industry experience) in molecular biology, biochemistry, genetics, cancer biology, immunology, or a related field
Deep understanding of cancer biology and experience working with publicly available datasets used to interrogate molecular mechanisms (e.g., TCGA)
Excellent cross-functional communication and teamwork skills, working with both computational and experimental scientists
Experience partnering with pharma in biomarker identification or companion diagnostics development
Experience working with liquid handling platforms for high-throughput research projects
Experience mentoring and training research associates
Senior Associate Scientist, Discovery Oncology, Organoid/3D Models
By Bristol Myers Squibb At San Diego, CA, United States
Experience in automation and screening a plus.
Manage cryopreservation of tissues and cell lines.
4+ years of academic and / or industry experience
2+ years of academic and / or industry experience
3D Model Systems experience with matrix-attached models, spheroids and/or organoids
Extensive in vitro cell culture experience including establishing new cells lines with CRISPR, lenti-virus, shRNA, and inducible expression systems.
Postdoctoral Scientist - Computational Protein Design
By BioSpace At San Diego, CA, United States
Literature review and investigation to identify key requirements on structure-based computational design for specific GPCR binding antibodies.
Great communication skills, (oral and written), along with a proven record of presentations and publications.
Experienced in research of GPCRs family would be highly desirable.
Hands-on experience in wet-lab techniques, coupled with a willingness to undertake training for additional wet-lab support tasks.
Experienced in molecular dynamics, simulation, physics-based computations or similar. (In particular of Rosetta).
Exceptional collaborative skills are a crucial, as the role requires working closely with a multi-functional team.
Protein Scientist Jobs
By MeliBio At Oakland, CA, United States

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Principal Scientist, Oncology Discovery
By Kimia Therapeutics At Berkeley, CA, United States
5+ years of relevant laboratory experience in cancer research, with a focus on small molecule drug discovery
Experience with mechanism of action studies for oncology drug discovery and validation in an industry setting
Strong understanding of the drug discovery process and demonstrated experience working on cross-functional teams
Experience with high throughput screening and hit validation techniques is a plus
Strong communication and interpersonal skills
Ph.D. in cancer biology, pharmacology, or related field
R&D Protein Purification Scientist
By IFF At Palo Alto, CA, United States
BS/MS and academic or industrial experience with protein purification and characterization. Candidates with a PhD may also be considered.
Experience in protein purification using ion exchange, size exclusion, affinity chromatography and other methods. Experience with FPLC systems, especially AKTA.
Background in protein science, biochemistry, bioanalytical chemistry, enzymology, or chemical biology.
Familiarity with modern analytical techniques and instrumentation for the analysis of proteins (e.g. UV/Vis, HPLC, SDS-PAGE, SEC).
Demonstrated hands-on problem solving, attention to detail, and critical thinking.
Discovery Pharmaceutics Scientist Jobs
By Johnson & Johnson At San Diego Metropolitan Area, United States
Excellent oral and written communication skills are required
Employees Are Eligible For The Following Time Off Benefits
Demonstrated ability to transform ideas into practical solutions is required
Ability to conduct laboratory experiments is required
Thorough understanding of physical and pharmaceutical chemistry principals is required
Learning agility is of high value and is required
Scientist, Translational Sciences, Immunology Translational Sciences And Medicine
By Johnson & Johnson At San Diego Metropolitan Area, United States
Detail oriented, highly organized multi-tasker with strong trouble-shooting skills.
Experience with the following molecular biology techniques/platforms is required: DNA/RNA/protein extraction, qPCR, NanoString, RNAseq and ELISA/MSD/Luminex/Singulex.
Immunologist with human-based tissue experience is highly preferred.
Experience with complex in vitro multi-cell assay systems (including tissue organoids, LPMCs and human biopsy explants).
Assay development experience using preclinical and clinical systems (including tissue, whole blood, and murine cells).
Experience with flow cytometric assays (examples include Symphony, CyTOF and cell sorting).
By At
Biomarker Discovery Scientist Jobs
By IDEXX At , Westbrook, 04092

What you need to succeed:

Maintenance Technician - Protein
By Cargill At , Milwaukee $24.65 - $36.60 an hour

Want to build a stronger, more sustainable future and cultivate your career? Join Cargill's global team of 155,000 employees who are committed to safe, responsible and sustainable ways to nourish the ...

Scientist, Bioanalytical Sciences Jobs
By Legend Biotech At Somerset, NJ, United States
Participate in assay development and qualification
Knowledge of cancer biology, and immunology and T-cell biology.
> 2 years’ experience in execution of cell-based and /or flow cytometry methods preferred.
Prior experience in CAR-T cell therapy development preferred.
Knowledge of Spectral flow cytometers and hands on human PBMC preparation preferred
Strong critical thinking and problem-solving skills
Scientist I - Discovery Biology
By UCB At Boston, MA, United States
Experience and working knowledge of concepts including but not limited to in vitro pharmacology, cell biology, molecular biology, histology/immunohistochemistry, FACS, etc.
Master’s degree with 6 years of relevant industry experience
Excellent communication skills with the proven ability to build collaborative relationships and work effectively as a member of a multidisciplinary team
Continuously develops more in-depth knowledge of UCB's drug discovery process through reading, conferences and seminars
Experience with culturing a broad variety of mammalian cells; proficiency with maintenance and differentiation of iPSCs is preferred
Experience training junior researchers is a plus (CoOps, Interns)
Scientist I - Rnai Discovery
By Novo Nordisk At Lexington, MA, United States
Experience with advanced in vitro model systems including organoids and other 3D culture systems is highly preferred
Experience with RNAi is preferred
Strong oral and written communication skills and a demonstrated ability to contribute effectively to group projects in a team-oriented environment
SiRNA drug candidate screening, hit identification, and lead optimization
Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays; PCR
In vivo drug candidate testing (e.g. mouse dosing; sample analysis)
Marketing Sciences, Data Scientist
By Sud Recruiting At United States
Full-time role that is fully REMOTE
Applied machine learning experience within marketing is a MUST
Must have applied machine learning experiences using Python
Exceptional critical thinking skills and abundant curiosity to innovate
full-time role that is fully REMOTE
applied machine learning experience within marketing is a MUST
Principal Scientist, Protein Engineering
By BioSpace At Durham, NC, United States
Work with multidisciplinary teams and program managers to achieve project milestones on time.
Experiences in high throughput screening and selection-based directed evolution for protein and guide RNA engineering in bacterial and/or mammalian cells.
Experience in early discovery in a CRISPR-based gene and cell therapy company is highly preferred.
Strong oral and written communication skills
Ongoing professional development, including manager training
Access to LinkedIn Learning, a self-guided online education platform
Scientist, Protein Characterization Jobs
By AstraZeneca At Gaithersburg, MD, United States
Masters with 1 year of experience or a BS with 3 or greater years of experience.
Hands-on experience running either a Biocore 8K or Carterra LSA.
Strong communication skills in a team environment and an ability to quickly learn and embrace new technologies
Experience with computational methods and machine learning applied to antibody/protein design and optimization
Experience of leading/co-leading and/or managing research projects
Track-record of development of new or improved high throughput protein expression processes.
Senior Director, Protein Sciences
By Arbor Biotechnologies At Cambridge, MA, United States
10+ years of relevant biotechnology or pharmaceutical industry experience in protein engineering, biochemistry, and structural biology.
5+ years of experience building, leading, and managing protein science teams to successfully meet objectives.
In depth knowledge of the enzymology CRISPR gene editing systems is essential.
Direct experience with state-of-the-art directed evolution methods in both bacterial and mammalian systems is required.
Knowledge of modern structural biology approaches including cryo-electron microscopy and X-ray crystallography.
Excellent collaboration, communication, and interpersonal skills.
Scientist, Protein Engineering Jobs
By BioSpace At Durham, NC, United States
Work on a multidisciplinary team using knowledge and experience in protein engineering to advance therapeutic programs.
Hands-on experience in conducting directed evolution campaigns.
Experience with molecular biology (PCR, cloning, library generation), specifically library generation
Experience with high throughput screening and selection methods such as FACS and/or display technologies
Research experience with genome editing technologies, nucleases, and/or DNA modified or DNA binding proteins is strongly preferred
Relevant technical skills for data analysis, DNA and protein sequence analysis, ELN documentation, and presenting results
Associate Scientist - Protein Purification
By Good Therapeutics, Inc. At Seattle, WA, United States
BS in a relevant scientific discipline with 3+ years of experience
Experience and proficiency with affinity, size exclusion chromatography and ion exchange chromatography
Prior experience purifying recombinant antibodies using Protein A chromatography is preferred
Prior experience with Cytiva AKTA preparative chromatography platforms and Agilent HPLC systems is preferred
Commuter benefit (ORCA Passport), parking
Purify protein drug candidates and related reagents to support multiple ongoing therapeutic programs
Research Associate, Protein Sciences
By BioSpace At Waltham, MA, United States
You have experience with protein expression and purification methodologies in mammalian cells
It is a plus if you have demonstrated experience with automation enabled high-throughput production and characterization methods
You pay attention to details and you practice rigorous scientific thinking & clear communication skills
Generous personal and family medical, dental and vision benefits with 90% of premiums and deductibles covered
Annual stipend for continuing education with commitment to your career through individualized professional development plan
You have a willingness to learn and innovate in a dynamic team first environment
Research Associate | Protein Sciences
By Alloy Therapeutics, Inc. At Waltham, MA, United States
You have experience with protein expression and purification methodologies in mammalian cells
It is a plus if you have demonstrated experience with automation enabled high-throughput production and characterization methods
You pay attention to details and you practice rigorous scientific thinking & clear communication skills
Generous personal and family medical, dental and vision benefits with 90% of premiums and deductibles covered
Annual stipend for continuing education with commitment to your career through individualized professional development plan
You have a willingness to learn and innovate in a dynamic team first environment
Scientist/Senior Scientist - Cystic Fibrosis Discovery And Development
By Drug-Discovery Startup At Cambridge, MA, United States
Inspire team members, provide feedback to group members and management team
Advanced knowledge of mucosal biology, lung diseases, cell/stem cell platforms
Lab experience includes many of the techniques and tools listed above
An experienced mentor who successfully fosters confidence and team commitment
2+ years of relevant postdoctoral employment experience
Preferred: 1-5 years of industry experience
Research Scientist - Microbial Discovery
By BiomEdit At Greenfield, IN, United States
Minimum Qualification (education, experience and/or training, required certifications):
·Knowledge and hands-on experience on microbiome research and NGS that include microbiome sample collection/inventory and microbiome profiling.
·Knowledge on basic bioinformatic skills (i.e. SQL, phyton/perl programming, genome assembly/annotation, microbiome analysis).
·Working experience with automation systems (e.g. liquid handler, automated DNA extraction platforms)
·Excellent oral and written communication skills
·Capability to manage multiple tasks and projects
Scientist I, Protein Engineering And Molecular Sciences
By Repertoire Immune Medicines At Cambridge, MA, United States
Independently design and execute experimental projects under the supervision of direct manager and scientific project leads.
M.S with 4 years of industry experience would also be considered.
B. S with 6 years of industry experience would also be considered.
Experience with protein display technologies required (e.g., yeast display, mammalian display, or phage display).
Experience with next generation sequencing and data analysis preferred.
Strong organizational skills, attention to detail, and data analysis skills are required.
Senior Scientist I, Biological Sciences
By Deciphera Pharmaceuticals At Lawrence, KS, United States
Other: Computer skills with MS Office (Excel, Word, PPT) and GraphPad Prism.
Generate transient and stable-transfected cell lines needed to understand activities of kinase inhibitors
Perform routine mammalian cell culture
Perform routine screening of small molecule kinase inhibitors
Responsible for analysis of samples from studies performed at CROs
Contributes to the identification and validation of new drug targets
Principal Scientist, Green Sciences Ingredients Innovation Advanced Research (Hybrid)
By L'Oréal At Clark, NJ, United States
Strong experience in project management and filing USPTO patents.
Strong interpersonal and organizational skills, and ability to manage multiple projects and priorities concurrently, detail-oriented, proactive and self-motivated
Lead and manage collaborative projects between external partners and internal laboratories to support concepts development and transformation.
Lead and manage collaborative projects between collaboration partners and internal R&I team to support concepts development and evaluation.
Manage multiple project tasks and priorities concurrently
Critical thinking and decision making skills to navigate complexed network and successfully drive projects forward.
Senior Scientist/Principal Scientist, Immunology Drug Discovery
By Jnana Therapeutics At Boston, MA, United States
Leverage drug discovery experience to impact Jnana's Immunology pipeline and strategy.
Experience and success leading drug discovery programs in the biotechnology/pharmaceutical industry, ideally with an auto-immune focused target.
Lead the biological efforts on established drug discovery projects
Represent Biology team in multi-disciplinary project teams to provide robust scientific and technical support; presentation at senior leadership meetings (internal/external).
Build screening funnels to identify emerging chemical matter, and contribute to the overall research and data communication strategy for key programs.
Interrogate novel biology to drive target identification and strategic prioritization of programs.