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[Research Associate / Associate Scientist], Programs

Company

BigHat Biosciences
Address , San Mateo, Ca
Employment type FULL_TIME
Salary
Expires 2023-06-24
Posted at 1 year ago
Job Description
The Role: BigHat Biosciences is seeking a self-motivated individual for a Research Associate or Associate Scientist* to contribute to and support research on multiple therapeutic optimization projects.

*At BigHat we believe in titles that are commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.

Key Responsibilities

  • Follow laboratory protocols, create SOPs, and keep a detailed record of all experiments using BigHat’s documentation tools.
  • Maintain cell cultures and assess activity of therapeutic antibody candidates using in vitro cell-based functional assays.
  • Contribute to key projects at BigHat by planning and executing of experiments to optimize antibody expression, stability, activity, and binding affinity.
  • Summarize results and critical problems in writing and in presentation to a collaborative, cross-functional team.
  • Contribute to the development and optimization of new assay types to be run at high throughput.

About You

About you:
Undergraduate or Master’s degree in the biological sciences; familiarity with protein biochemistry; lab experience with ELISA, Western Blot, or SDS-PAGE; strongly self-motivated individual with attention to detail; driven, team-oriented, and excited to work in a dynamic startup environment.
Nice to haves:
  • Ability to manipulate and analyze data in R/Python
  • Prior experience with cloning and mammalian cell culture
  • Hands-on knowledge of protein expression and purification
  • Experience with ELISA/immunoassay and BLI/SPR
  • Familiarity (or interest in) operating automated liquid handlers
  • Bachelor’s degree in immunology, genetics, or biochemistry

About BigHat Biosciences

BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology.
BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.

BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC.

Apply Now