Senior Research Associate/Associate Scientist, Age-Related Neurodegenerative Disease

Deciduous Therapeutics is an early stage, venture-backed biotech company based in San Francisco, California developing novel therapies that activate the endogenous immune biology responsible for treating senescence in age-related diseases.

We are looking for a highly ambitious and talented Senior Research Associate/Associate Scientist to join our central nervous system research team and play a critical role in our research and drug discovery efforts.You will have the opportunity to be an early team member and generate key experimental data for highly intersectional studies with a focus on neurological disorders. There is significant opportunity to shape your role and advance within the company while growing as a researcher and leader.We are a small, hardworking team that is passionate about delivering important medicines that could significantly impact how we age.

Key Responsibilities and Job Functions

• Neuroimmune cell in-vitro and in-vivo functional and molecular studies (surface marker expression, migration, cellular cytotoxicity, cytokine secretion) using multi-color flow cytometry, ELISA, Luminex, Immunoblotting, Immunofluorescence and qPCR
• Systemic biomarker collection and analysis, including cardiometabolic, renal and hepatic function
• Conduct in-vivo experiments in support of novel target validation, engagement & optimization including PK-TE, PK-PD, and functional efficacy endpoints
• Analyze workflows and assay performance to increase efficiency and maintain scientific rigor
• Assist with vetting appropriate CROs and play a key role in study design and monitoring execution

Qualifications and Skills

• Experience with multiple methods of tissue culture, processing, and analytical analysis (flow cytometry, ELISA, Immunoblotting, qPCR, Immunofluorescence)
• B.S. or M.S. in relevant discipline with 3-7 years of industry experience (neuroscience or metabolic background is preferred)
• Eligible to work in the United States
• The ideal candidate is entrepreneurial, energetic and well-suited to adapt to and shape a dynamic environment
• Experience developing and executing rodent disease model studies (IACUC submission, study design and execution, data analysis and presentation, data archiving)
• Familiarity with or direct animal behavioral experience including motor function, spatial learning and memory, and anxiety
• Technically proficient with a track record in many aspects of in vivo rodent research (dosing routes, anesthesia, necropsy, tissue processing, etc).

Compensation

We offer a competitive salary, stock options, and health benefits. In addition, we provide a monthly activity stipend to cover a gym membership or other hobbies of interest.

Furthermore, we are a company that strongly believes in fostering the intellectual advancement of our team. As such, we support career development opportunities (online courses, seminars, conferences) that intersect with areas of interest for the company.

We value diversity of personal identity, experience, and thought. We will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.