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Principal Scientist / Computer-Aided Drug Design (Cadd)
Company | UCB |
Address | Cambridge, MA, United States |
Employment type | FULL_TIME |
Salary | |
Category | Pharmaceutical Manufacturing |
Expires | 2023-10-23 |
Posted at | 9 months ago |
Make your mark for patients.
- Independently design and execute computational experiments in a timely manner to enable the progression of therapeutic projects with a special focus on targeted protein degraders.
- Build a culture of data-driven decision making through the judicious application of recent advances in property predictions & generative molecular design methods.
- Create effective working relationships & interface across multiple internal disciplines – IT, DMPK, Safety, Chemistry & Data Sciences and beyond via influencing and networking.
- Champions effective optimization of drug discovery processes through application of physics-based approaches, data-driven predictive methods and AI-based design methodologies. Effectively solicits input and feedback and drives innovation.
- Contribute to CADD technology acquisition, development, implementation and applications to pipeline projects through effective project management and cross-functional collaboration.
- Demonstrates strategic thinking for project delivery, identification and implementation of the next disruptive technology in order to stay at the forefront of drug discovery.
- Proven scientific leadership and excellent communication skills. Acts as an ambassador for CADD by providing scientific expertise / leadership at cross-disciplinary meetings and departmental meetings.
- Proven track record of accelerating drug discovery through application of physics-based approaches, machine learning and data analytics/science.
- PhD in Chemistry, Computational Chemistry, Molecular Modeling or a related field is required with a good publication/patent track record.
- 12+ years of drug discovery experience, working across multiple therapeutic areas including neuroscience, immunology therapeutic including project leadership roles.
- Excellent knowledge in applying principles of medicinal chemistry including the design of TPDs toward drug discovery.
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