Scientist Discovery Protein Sciences

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents. We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

The successful candidate will play a key role in the downstream purification function within the Discovery Protein Science group, supporting a wide range of therapeutic programs. Responsibilities will be focused on biologic drug candidate developability including platform suitability and non-platform process development. Additional responsibilities will include drug candidate generation spanning multiple modalities as well as reagent generation in support of early stage Discovery programs.

• Deliver on reagent requests to support Discovery programs.
• Perform mid-scale purifications for the evaluation and comparison of early Discovery therapeutic candidates.
• Support upstream mammalian and bacterial expression efforts.
• Protein production for mid-stage Discovery programs to support cyno tox studies, concentratability, PK/PD, formulation/analytical development etc.
• Support downstream purification efforts (reagents & therapeutics), with a focus on process design, implementation, optimization and troubleshooting. Develop scaleable, phase appropriate purification processes for non-platform drug candidates.
• Troubleshoot downstream purification processes and chromatography instrumentation.
• Participate in the preparation of technical reports, summaries, protocols, and regulatory documents, where necessary.
• Contribute to the continuous improvement effort for the Discovery manufacturability assessment in collaboration with Manufacturing Development.
• Perform platform suitability and manufacturability assessments as part of enabling package for therapeutic candidates transitioning to the manufacturing development organization.

Basic Qualifications

• OR Master's Degree in a scientific discipline 3+ years of academic / industry experience
• OR PhD in a scientific discipline No experience required
• Bachelor's Degree in a scientific discipline and 5+ years of academic / industry experience

Preferred Qualifications

• Protein purification experience including method development, optimization, and the ability to troubleshoot standard purification protocols and instrumentation.
• Experience with larger scale protein production (CMC, and tech transfer experience is a plus).
• Protein characterization experience (biophysical, spectroscopy, protein assays, SDS-PAGE)
• Hands on experience in the operation and control of chromatography workstations (AKTA, BioRad, etc.).
• Experience with LIMS and Electronic Notebook is a plus.
• Excellent communication skills, evidence of innovative thinking, and ability to work with a sense of urgency under tight deadlines.
• Excellent technical, organizational, and analytical skills are required.
• B.S. in a scientific discipline and at least 5 years of relevant laboratory experience or M.S. with at least 3 years of relevant experience preferred.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.