Research Associate/ Associate Scientist, Bioanalytical

Waltham MA

Full Time |

The Company

We are Alloy Therapeutics—a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of its revenue in innovation and access to innovation. MAY THE BEST DRUG WIN.

Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, CH; San Francisco, CA; and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. Come thrive at Alloy!

The Team

The Alloy Global Bioanalytics group provides bioanalytical support to all Alloy activities, including assay development, quality control and high-throughput characterization of antibodies, TCRs, TCR mimics and other modalities.

The Role

As a Research Associate/ Associate Scientist, Bioanalytical, you will work with our Discovery Services team and KeywayTM TCR Discovery team to support the discovery of antibody-based therapeutics and of novel T cell receptors (TCR) biotherapeutics. You will be using the very latest protein analytics tools and protocols with the ultimate goal of helping others to make better medicines. This role requires an enthusiasm for biochemical and biophysical characterization of antibodies, TCRs and peptide Human Leukocyte Antigen complex (pHLA).

This is you!

How You’ll Drive Impact

• Collaborate: Collaborate with Scientists on assay design and execution
• Improve: Learn and identify key questions in the field
• Support: Perform and support biochemical/biophysical characterization (e.g., protein purity, aggregation, charge variance); binding characterization (e.g., protein-protein interactions, cell binding, ligand inhibition assays), and developability assessment (e.g., thermostability, self-interaction, poly-reactivity)
• Innovate: Look for new ideas, assays, or tools for analytical evaluation of biotherapeutics
• Deliver: Robust, high quality data analysis to the team

Why We Value You

• You have experience with charge analysis (cIEF or CZE), size and purity analysis (CE-SDS, SEC HPLC, DLS), or mass spectrometry
• You have experience with Flow Cytometry, SPR or BLI, SEC HPLC
• You display a strong command of the fundamental principles of analytical chemistry
• You have a track record of troubleshooting instruments
• You have excellent written and oral communication skills
• You have a B.S. or M.S. degree in a relevant scientific field (e.g., biochemistry, chemistry, molecular biology etc.)
• You have an independent sense of urgency, persistence, and integrity
• You have ELN and LIMS experience
• Your ability to multitask and accomplish goals under project and team timelines
• You have a proven understanding of protein biochemical properties and protein-protein interactions

Desired Multipliers

• Attention to detail
• Accommodate occasional travel as needed (<5%)
• Excitement and willingness to learn
• Ability to work across various US and international time zones

Taking Care of Our People
We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you’re single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one.
Compensation

• 401(k) company match and financial planning
• Unlimited PTO (paid time off) and flexible schedules
• Competitive base and equity compensation

Health & Family

• Company-paid disability (STD, LTD) and life insurance
• Paid parental leave
• Generous personal and family medical, dental and vision benefits with 90% of premiums and deductibles covered
• Family planning support up to $50,000 (e.g. IVF/PGT, adoption, surrogacy, egg retrieval)

Unique Perks

• International travel insurance
• Flexible work schedule built around our team-driven philosophy
• Extensive Employee Assistance Program (EAP) including resources for mental wellness
• Annual stipend for continuing education with commitment to your career through individualized professional development plan

Diversity, Equity, and Inclusion
Here at Alloy, we democratize capabilities for discovering and developing therapeutic biologics. So, being diverse and inclusive isn’t just something we strive for, it is who we are, and part of what we do each and every single day. We want to ensure that as an employee, you feel Alloy is a place where, no matter who you are, you feel safe, included, and that you have the opportunity to bring your unique self to work.
Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected]. We will make every effort to respond to your request for disability assistance as soon as possible.
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