Research Associate Scientist, Cell Therapy Innovation

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Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?
At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Here, you will be a vital contributor to our inspiring, bold mission.
OBJECTIVES/PURPOSE/ SCOPE
This opening is an opportunity to be part of an excellent team focused on accelerating cancer cell therapy development using the latest technologies. As a Senior Research Associate your major role will be to contribute to the creation of cellular treatment platforms using primary gdT cells and NK cells. You will be responsible for organizing and executing procedures to characterize and produce data for target selection and product design for various cell therapy discovery programs. Apart from drafting technical documents, such as SOPs and study reports you will also responsible to present study findings at team or department meetings, as well as to partners outside the company or at conferences.
Accountabilities

• Demomstrate fundamental understanding of science and technology outside of a particular subject
• Understand the rationale behind the selection of a set of experiments
• Independently conducts multiple complex experiments and/or tasks within a project scope, exercising judgement to evaluate a variety of technical factors, and obtain optimum solutions
• Work with departmental and peers to implement assignments.
• Recognizes problems and considers the significance of irregularities
• Demonstrate comprehensive understanding of the given research techniques
• Use your expertise in laboratory technology to mentor and educate junior personnel while collaborating with other departments and colleagues on projects.
• Develop intricate experimental protocols and advance the project while internally analyzing, interpreting, and reporting findings to managers and project teams.
• Implement project assignments in conjunction with coworkers and departmental teams, taking ownership of the technical components of the task.
• Receives high-level instructions for all tasks; decides on own how to approach new assignments; mentors and may supervise subordinate staff
• Design experiments and unit operations independently, offer and implement solutions to technical problems, assist in creating project strategies, and effectively communicate complex information and judgments.

Education, Behavioural Competencies And Skills

• Experience with non-viral gene delivery systems using EP, cell transfection, virus transduction, and CRISPR gene editing is strongly preferred (Electroporation).
• Knowledge of the fundamentals and techniques of cell biology methodologies, cellular immunology, including cell culture, viral transduction (retroviral or lentiviral), and the creation of practical in vitro and preclinical techniques applicable to various immune cells or stem cells.
• Working knowledge of creating cell therapy products like CAR-NK, CAR-abT, CAR-gdT, or iPSC-derived cells, or working knowledge of carrying out cellular characterization assays like multicolor flow cytometry, multiplexed luminescent readouts, Incucyte, in vitro proliferation/apoptosis, killing assays, and cytokine detection.
• Experience with CliniMACS Prodigy, CliniMACS plus, LOVO, or Sepax is a plus.
• MS in a scientific discipline (or equivalent) with 3+ years relevant experience, or BS with 5+ years relevant experience
• Proven proficiency in growing primary gdT or NK cells.
• Previous experience working in lab setting.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
What Takeda Can Offer You

• 401(k) with company match and Annual Retirement Contribution Plan
• Tuition reimbursement Company match of charitable contributions
• Health & Wellness programs including onsite flu shots and health screenings
• Community Outreach Programs
• Generous time off for vacation and the option to purchase additional vacation days

Base Salary Range 82,000 to 125,000.00. Employees may also be eligible for Short Term and Long-Term Incentive benefits. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.
The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.
Empowering Our People to Shine
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EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
Boston, MA
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time