Research Associate - Biochemistry & Biophysics

At Foghorn Therapeutics, we believe in “People First, Mission Always.”

We put “People First” because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics – demonstrated by our community speaking more than 22 languages and representing over 24 nationalities. We value our teammates as people, not just as employees – validated by our actions that let our people know that we care about them, their families, and their lives.

We say “Mission Always” because we know a relentless commitment to our mission will make a difference in the lives of others. We believe our success will come from evaluating the data to follow the science. We work hard to develop a new class of therapies that could improve the lives of over 2.5 million people with cancer.

Our culture is focused on succeeding through the evaluation of data, not people. And in that, relationships can flourish and develop.

Our Science:

The groundbreaking science behind our therapies continues to yield vital insights into diseases that have confounded physicians and researchers. Our core scientific approach is centered on the chromatin regulatory system, which opens and closes the right sections of DNA at the right time. Breakdowns in the chromatin regulatory system lead to a wide range of diseases, including cancer, impacting millions of people.

Our proprietary Gene Traffic Control® platform is a powerful tool for understanding and modulating the chromatin regulatory system. We are pursuing multiple treatments for breakdowns in this system. We are the only company with the ability to study and target the chromatin regulatory system at scale, in context, and in an integrated way.

Learn more about Foghorn at www.foghorntx.com.

Job Summary

Foghorn is seeking a highly motivated, enthusiastic, and collaborative Research Associate to join our Drug Discovery team in a lab-based role to support early discovery projects in oncology. As a member of our Drug Discovery team the candidate will have an opportunity to employ various biochemical and biophysical assay technologies in mechanism of action studies, screening and hit validation. This is an onsite and lab based role.

Key Responsibilities

• Work collaboratively as part of multidisciplinary team and present results to project teams
• Design, develop and troubleshoot in vitro biochemical and biophysical assays for both protein-protein and small molecule-protein interactions
• Profile compounds to support hit validation and lead optimization efforts
• Analyze, interpret, and document data using an Electronic Laboratory Notebook and data analysis software tools

Requirements

Minimum Qualifications

• BA/BS in Biochemistry, Biophysics, or related field
• 1+ year Lab experience in academia or industry
• 1+ year experience with fluorescence-based assay techniques

Preferred Qualifications, Skills, And Competencies

• Ability to learn new techniques quickly and a focus on attention to detail
• Familiarity with automated liquid handling instrumentation is a plus
• 2+ years of experience with fluorescence-based assay techniques (e.g., HTRF, FP, Alpha) and label-free technologies (e.g., ITC, DSF, SPR, MST) is desired
• 2+ years of relevant lab experience in biotechnology industry
• Excellent communication and inter-personal skills with ability to work collaboratively on cross functional teams
• MS degree in Biochemistry or Biophysics
• Cell culture skills and experience with cell-based assays is a plus
• Demonstrated ability to analyze, interpret and present data in a clear manner

Benefits

Foghorn Therapeutics is pleased to provide you and your family with a comprehensive suite of benefits, including:

• Generous Paid Leave offerings, including 12 weeks of 100% paid parental leave
• Unlimited paid time off policy
• FSA and HSA for medical expenses and dependent care expenses
• Free premium access to fitness, nutrition, and mindfulness classes
• Free parking or subsidized commuter passes
• Paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Highly competitive and inclusive medical, dental and vision coverage options
• Discretionary winter shut down
• 401k retirement plan with company match