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Associate Scientist, Precision Editor Screening

Company

Arbor Biotechnologies

Address Cambridge, MA, United States
Employment type FULL_TIME
Salary
Category Biotechnology Research
Expires 2023-08-09
Posted at 10 months ago
Job Description

Who are we?

We are a next-generation gene editing company focused on discovering and developing potentially curative genomic medicines, with the most extensive toolbox of proprietary genomic editors in the industry. We have the unique ability to work backward from disease pathology and choose the optimal editors or combination of editors for the disease in question. Find out more at arbor.bio.


Who are you?

Passionate, determined, and accountable. Curious, resourceful, innovative, forward thinking, and resilient. Authentic, humble, open-minded and puts team above self. At Arbor, our people embrace these qualities, so if this sounds like you then please read on!


The Precision Editing team at Arbor Biotechnologies is looking for an Associate Scientist interested in applying and advancing novel precision editing technologies to develop therapeutic gene-editing products. In this role, you will develop, optimize, and characterize next generation gene editing systems in disease relevant human cell models to support Arbor’s innovative pipeline of gene editing therapies. We are looking for a scientific contributor that has a strong background in mammalian cell biology, cellular assay development, and understanding of drug development. Additionally, familiarity of molecular biology and cloning and knowledge of next generation sequencing and flow cytometry is a plus.


What can you expect?

  • Articulate data and results to research teams and other company forums with clarity and precision.
  • Collaborate with automation and computational biology teams to help improve methods for data collection and analysis.
  • Contribute to innovation initiatives aimed at amplifying the efficacy of cutting-edge gene editing technologies in mammalian cells, collaborating closely with the protein engineering team.
  • Analyze data and maintain laboratory notebooks to ensure documentation of experimental results.
  • Lead the design of studies to assess gene editors, skillfully execute experiments, and proficiently analyze and interpret data.
  • Pioneer development of methods to thoroughly characterize groundbreaking gene editing systems in mammalian cells utilizing molecular and functional readouts.


What you bring:

  • Experience with cell culture, transfection, PCR, Western blot, reporter assays and fluorescent imaging.
  • Detail-oriented with excellent organizational and communication skills.
  • Experience in mammalian cell-based assay development.
  • Familiarity with next generation sequencing and the use of automation in the context of cell screening in a bonus.
  • Familiarity of molecular biology and cloning is a plus.
  • Understanding of gene editing in mammalian cell systems is desirable.
  • Familiarity with programs such as Excel, GraphPad Prism, and PowerPoint for data presentation.
  • Experience with flow cytometry is a plus.
  • MS 6+ years’ experience or BS and 8+ years of equivalent training in cell biology, genetics, or related bioscience field.
  • Strong collaborator within cross functional teams.
  • Ability to adapt in a fast-paced environment.


We promote diversity and inclusion not just in our recruitment processes, but in everything we do. We’re an equal opportunity employer and we will continue to ensure our recruitment process is free of bias and our workplace is inclusive, positive, and free of discrimination and respecting of all backgrounds and beliefs.