Associate Scientist, In Vivo Pharmacology

Who We Are
At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.
What We Do
Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company’s diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson’s disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie
About The Role
As a member of the In Vivo Biology Research team, this individual will focus on in vivo support to translational research efforts and generate nonclinical data packages that support Neurocrine’s mission of developing novel therapeutics for patients with great unmet need. The candidate will perform assigned experiments to support scientific activities in mice and rats with compound formulation and dosing using various routes of administration, behavioral testing (motor, cognitive, etc.), tissue collection, and data analysis. They will be directly involved in assay development for in vivo examination of novel drug targets and screening of potential therapeutic compounds, study design, execution of procedures, and data communication in a team setting.
_
Your Contributions (include, But Are Not Limited To)

• Provides training and/or supervision to junior staff, as needed
• Completes data analysis and reporting. Maintains and updates SOP’s and writes data summaries for experiments conducted
• Handles and doses animals in a laboratory setting
• Follow study protocol, IACUC protocols, SOP and animal welfare policy in animal studies. Help maintain laboratory and supply inventories
• Perform all duties in keeping with the Company’s core values, policies and all applicable regulations
• Administer small molecule compounds and biologics to naïve and disease-model rodents (mouse and rat), measure endpoints (body weight, clinical scores, behavioral) and collect biospecimens
• Reviews, comprehends and complies with all SOP’s, IACUC procedures, and safety and quality assurance standards at all times
• Have effective troubleshooting, problem-solving and communication skills
• Performs assigned experiments to support scientific activities and project goals involving in vivo pharmacology assessment of novel therapeutics
• Recommends alternatives, researches new methods and techniques and may proactively seek out senior personnel to discuss potential solutions to problems
• Collect, organize, and present scientific/technical data internally and in project team meetings
• May design less complex experiments
• Works with stereotaxic surgical techniques
• Oversees compound dosing via multiple routes of administration
• Work both independently and collaboratively. Candidates must be flexible and have strong multitasking skills
• Independently execute in vivo PK/PD and/or efficacy studies that support nonclinical and clinical stage programs in the neurology and endocrinology disease space
• Other duties as assigned
• Responsible for behavioral assay development, validation and screening

Requirements

• High level of organization and attention to detail
• Extensive hands-on knowledge of behavioral testing in a variety of assays
• Ability to meet deadlines
• Good project management skills
• Working knowledge of stereotaxic surgery, AAV administration and/or mouse colony maintenance and breeding
• Good knowledge of scientific principles, methods and techniques
• Good communications, problem-solving, analytical thinking skills
• Advanced multitasking, trouble shooting and deductive reasoning skills required
• BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and 2+ years of experience in the handling and dosing of rodents in a laboratory setting OR
• Previous experience with stereotaxic surgery, AAV administration and/or mouse colony maintenance and breeding preferred
• Must have working knowledge of Microsoft Office, Word, and Excel
• Willingness and ability to work both independently and as part of a team
• Occasional weekend work required
• Strong knowledge of one scientific discipline
• Strong computer skills
• MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred
• Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
• Recognizes fundamental anomalies in data points and identifies issues in experiments/processes
• Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools

Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.
We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.
_
The hourly rate we reasonably expect to pay is $32.99-$51.16. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 15% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.