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Scientist Principal Jobs in Middlesex, Massachusetts

Senior Scientist/Principal Scientist, Cell-Based Assays
By Garuda Therapeutics At Cambridge, MA, United States

Garuda Therapeutics, a biotechnology company focused on developing off-the-shelf human hematopoietic stem cell-based cellular therapies, is seeking a highly motivated senior / principal scientist to ...

Principal Scientist / Computer-Aided Drug Design (Cadd)
By UCB At Cambridge, MA, United States
Contribute to CADD technology acquisition, development, implementation and applications to pipeline projects through effective project management and cross-functional collaboration.
12+ years of drug discovery experience, working across multiple therapeutic areas including neuroscience, immunology therapeutic including project leadership roles.
Excellent knowledge in applying principles of medicinal chemistry including the design of TPDs toward drug discovery.
PhD in Chemistry, Computational Chemistry, Molecular Modeling or a related field is required with a good publication/patent track record.
Proven track record of accelerating drug discovery through application of physics-based approaches, machine learning and data analytics/science.
Make your mark for patients.
Senior Scientist/Associate Principal Scientist, Analytical Development
By Alkermes At Waltham, MA, United States
Manage all aspects of the GMP stability storage operations and ensuring compliance with internal procedures, industry regulations, and regulatory guidelines
Expertise and experiences in liquid chromatography and GC method development and validation is required
Demonstrated leadership skills and excellent verbal and written communication skills are essential
Excellent interpersonal and team skills are required
The ability to work in a fast-paced environment, manage priorities, and maintain timelines for multiple activities are required
Good interpersonal and communication skills
Principal Scientist, Pharmacometrics Jobs
By Moderna At Cambridge, MA, United States
Strengthen our pharmacometric capabilities on a continuous basis by evaluating and incorporating new M&S tools and initiating trainings as appropriate
PhD with a focus in pharmacokinetics, pharmacology, pharmaceutics or other related field with 6+ years of drug development experience
Deep and broad experience in clinical and non-clinical drug development with in-depth expertise in quantitative clinical pharmacology and translational medicine
Requires effective skills directed toward driving teamwork, accomplishing results, influencing, and resolving problems across internal and external project teams
Excellent interpersonal, verbal and written communication skills and the ability to function in a highly matrixed team environment are essential.
Family care benefits, including subsidized back-up care options and on-demand tutoring
Principal Scientist, Respiratory Delivery, Drug Product Development
By Moderna At Cambridge, MA, United States
Experience in project management approach to advance complex and fast-paced projects through matrixed (internal and external) teams
Perform required risk assessments, implement appropriate mitigation strategies, and document approaches through appropriate risk management systems
Manage external vendors to evaluate device technologies
Minimum of 8 years (PhD), 10 years (MS), 14 years (BS) industry experience in pulmonary and/or nasal drug delivery
Strong written and oral communication skills
Family care benefits, including subsidized back-up care options and on-demand tutoring
Principal Scientist, Chemoproteomics Jobs
By Matchpoint Therapeutics At Boston, MA, United States
Qualifications/ Education Requirements / Competencies
6 years' experience in nano-scale proteomics methodology employing Thermo Fisher Orbitrap mass spectrometers with additional skill sets required.
Key Responsibilities / Essential Functions
Implement Tandem Mass Tag (TMT)-based quantitative proteomics to elucidate precise interaction between small molecules and proteins.
Develop data dependent acquisition (DDA) MS methods and targeted proteomics-based methods.
Design and execute experiments profiling Post Translational Modifications in intact cells, tissue or cell-culture lysates.
Senior Scientist/Principal Scientist, Immunology Drug Discovery
By Jnana Therapeutics At Boston, MA, United States
Leverage drug discovery experience to impact Jnana's Immunology pipeline and strategy.
Experience and success leading drug discovery programs in the biotechnology/pharmaceutical industry, ideally with an auto-immune focused target.
Lead the biological efforts on established drug discovery projects
Represent Biology team in multi-disciplinary project teams to provide robust scientific and technical support; presentation at senior leadership meetings (internal/external).
Build screening funnels to identify emerging chemical matter, and contribute to the overall research and data communication strategy for key programs.
Interrogate novel biology to drive target identification and strategic prioritization of programs.
Research Principal Scientist Jobs
By BioSpace At Boston, MA, United States
Frequent contact with internal and external personnel at various management levels
Broad knowledge in molecular biology, cell biology and immunology, especially in immuno-oncology cell therapy field required.
Experience with CAR-T, CAR-NK or other CAR-based immune effector cell therapies required.
Direct experience in CAR/CCR construction design, optimization and functional validation required.
Experience with CB-NK and/or γδT cells preferred but not required.
Excellent written and verbal communication skills, detail-oriented organization skills, and team collaboration skills required.
Principal Research Scientist Jobs
By Northeastern University At Boston, MA, United States

About The Opportunity Provides scientific and technical leadership in the management, design, and conducting of the entire research program within the WIoT Institute. Responsibilities include ...

Principal Data Scientist Jobs
By Intuit At Mountain View, CA, United States

Intuit is hiring a Principal Data Scientist to join our Intuit AI team. Come join our collaborative and creative group of data scientists and machine learning engineers and build models that ...

Senior Scientist/Principal Scientist, Molecular And Cellular Pharmacology
By Arrowhead Pharmaceuticals At San Diego, CA, United States
Experienced in RNA isolation, real-time PCR, RNA-seq
Hands-on experience with cell culture and FACS cell sorting
Design and execute in vitro and in vivo studies to facilitate drug discovery and platform development in various disease areas
Develop, validate, and perform assays to characterize ligand-receptor interactions and to gain mechanistic understanding of drug delivery
Present research findings to project teams and governance bodies and prepare study reports
Maintain a high level of productivity in the lab and perform critical experiments
Principal Research Scientist Jobs
By ecocareers At Berkeley, CA, United States

Company Overview Plastic is one of the most important inventions of the last century. They were intended to be useful, cheap, and durable. But right now, they are leaking into every aspect of our ...

R&D Principal Scientist
By Ornua At Hilbert, WI, United States
Lean Six Sigma experience/certification or likewise
Technical knowledge of standardized/non-standardized processed cheese or imitation cheese
Experience working in application lab, pilot plant systems and with laboratory instrumentation.
Experience working in Food industry - B2B product development, formulation, and commercialization of cheese/dairy/food products
Experience or familiarity working with starch systems, protein matrices and/or plant-based cheese
Culinary experience designing custom applications with custom cheese ingredients will be a plus
Principal Scientist Jobs
By PROLIM Corporation At Rochelle, IL, United States
Required Education, Experience, and Skills:
Preferred Education, Experience, and Skills:
Strong working knowledge and experience working with industrial minerals and chemical additives
Support and mentor less-experienced colleagues. Direct the work of technicians.
High level of knowledge of physical chemistry and powder technology
Experience conducting trials in a laboratory, pilot plant, or plant environment
Principal Scientist Ii (Qc)
By Cambrex Corp. At , Durham
Learn new skills and enjoy new experiences in an engaging and safe environment
Communicates issues or challenges to senior staff and/or management
learn new skills and enjoy new experiences in an engaging and safe environment
Able to apply prior knowledge to accurately interpret structural data.
Participates in experimental design, including development of methods and testing requirements to demonstrate method suitability.
Assists with writings standard operating procedures (SOPs), methods, qualification protocols and other standard documents as directed
Principal Jobs
By Catapult Learning At Plainview, TX, United States
Utilize school’s behavior management and intervention strategies including but not limited to de-escalation techniques, crisis management, and PBIS strategies.
Collaborate with facilities management to address maintenance and infrastructure needs.
Extensive experience with students with disabilities strongly preferred
Comprehensive benefits package including medical, dental, vision, and 401K matching
Ensure that all students are being educated in accordance with their Individualized Education Plans (IEPs)
Collaborate with the finance department to prepare financial reports and forecasts, providing regular updates to the school administration.
Principal Jobs
By Mobile County Public Schools At , $91,572 a year
Participates in cutting edge school reform initiatives that combine proven business and education management strategies.
Provides effective leadership in planning, developing, implementing, and evaluating the instructional program, technology management, fiscal leadership/management, and school operations.
Must have a valid Alabama Certification in Educational Administration, Educational Leadership, or Educational Supervision.
Prepares and administers the school budget and supervises school finances.
Must have a minimum of three (3) years of teaching experience.
Must submit all qualifications and credentials by the established deadline.
Principal Membrane Scientist Jobs
By Carlisle Construction Materials At Carlisle, PA, United States
Project management skills in a cross functional environment
Supporting the EPDM roofing business through new product development, processing and performance improvement, raw material qualification and cost reduction projects.
Experience in the development of rubber products and their associated processing technologies such as mixing, extrusion and calendaring are a plus
Theoretical and practical knowledge of the physical, chemical, and mechanical behavior of the thermoplastic polymers
Knowledge to analyze data, understand structure property relationships of polymers and conduct relative testing and evaluations
Experience with FTIR, DSC, TGA and rheology analysis of polymers
Principal Jobs
By St. Landry Parish School Board At , Opelousas, 70570

TITLE: Principal (FLSA EXEMPT) Qualifications: In accordance with the requirements of the Louisiana Department of Education. Reports to: Superintendent Supervises: All school personnel ...

Principal Scientist / Senior Research Scientist- Personal Care
By Colgate-Palmolive At , Piscataway $100,000 - $147,000 a year
Possess strong project planning/prioritization and management, analytical decision making and organizational skills
5+ years of experience developing and/or implementing consumer products with a PhD or 10+ years with a Masters Degree
Able to multi-task and manage multiple projects concurrently
Strong oral and written communication skills
Knowledge of polymer chemistry, material science, surfactant/colloid chemistry, and/or analytical sciences
Possess technical knowledge in one or more of the following areas: surfactants, active agents, delivery systems, rheology and statistics/experimental design
Principal Biostatician Jobs
By Novartis At , Cambridge $136,800 - $205,200 a year
Collaborate cross-functionally (e.g. data management, programming, medical writing) to ensure timeliness and quality of statistical deliverables.
PhD with 3+ years’ experience preferred OR MS with 7+ years’ experience
Good communication and presentation skills
Responsible for all statistical tasks on the assigned trials.
Protocol development in alignment with the development plan, developing statistical analysis plan, reporting activities.
Contribute to planning and execution of exploratory analyses and statistical consultation within your cross-functional teams.
Principal Scientist: Program Team Lead Preclinical Research
By Novartis At , San Diego $118,000 - $177,000 a year
Experienced scientist with 3+ years’ experience in the drug development process and 1+ years’ people management experience
Presentation of data and strategy to the internal management boards and external scientific presentation at conferences and meetings.
Experience as lab group leader with hands-on skills preferred
Excellent oral and written communication skills across all levels within and external to the organization
Experience with genetic medicine therapeutic approaches preferred
Experience with CNS disorders preferred
Principal Data Scientist Jobs
By GSK At Philadelphia, PA, United States
Collaborate with cross-functional teams to understand business requirements, identify opportunities for data-driven insights, and translate these into actionable solutions.
7+ years of experience in data science, machine learning, or advanced analytics roles.
Experience with AI, large language models, and machine learning techniques, including supervised and unsupervised learning, natural language processing, and deep learning.
Experience with big data technologies, such as Spark, and cloud platforms, such as Azure.
Strong programming skills in Python, R, or other relevant languages.
Exceptional communication and presentation skills, with the ability to convey complex ideas in a clear and concise manner.
Sr. Principal Scientist - Quality Control Compliance
By Lilly At , Branchburg, 08876
Strong problem-solving skills with experience in Root Cause Analysis.
Interacts effectively with business partners to communicate and resolve issues. Understands business requirements of the other functions.
Master/PhD in Chemistry, Biochemistry or related science with a minimum of 5-10 years’ experience in a cGMP (analytical or biology) environment.
Prior experience working in a GMP analytical laboratory with demonstrated proficiency in complex laboratory analysis.
Understanding of compliance requirements and regulatory expectations.
Experience with a broad range of analytical techniques applicable to monoclonal antibodies, including (cell-based) bioassays, qPCR and ELISA methods.