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Senior Scientist - Ipp Structural Biology

Company

Amgen

Address , Thousand Oaks, Ca
Employment type FULL_TIME
Salary $120,669 - $144,385 a year
Expires 2023-10-06
Posted at 9 months ago
Job Description
Career Category
Scientific
HOW MIGHT YOU DEFY IMAGINATION?
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Senior Scientist - IPP Structural Biology
Live
What you will do
Let’s do this. Let’s change the world. In this vital role you will join the Structural Biology Department at our site in Thousand Oaks, CA. The Structural Biology laboratory provides comprehensive molecular insights and structure-based design for drug-target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various therapeutic areas.
Responsibilities:
  • Interact directly with small molecule scientists including computational scientists, medicinal chemists, and protein engineers.
  • Work closely with molecular biologists and protein biochemists in the protein expression group.
  • Must be flexible to apply their knowledge to new areas of study, with strong interpersonal and communication skills to thrive in a highly collaborative environment.
  • Responsible for structure determination of target molecules in our small molecule induced proximity platform (IPP) using X-ray crystallography and/or cryo-electron microscopy (cryo-EM).
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a driven individual with these qualifications.
Basic Qualifications:
  • Doctorate Degree or
  • Master’s degree and 4 years of structural biology and general biochemistry experience or
  • Bachelor’s degree and 6 years of structural biology and general biochemistry experience
Preferred Qualifications:
  • Proven expertise on protein crystallography and/or cryo-EM single particle analysis, to determine atomic resolution structures
  • Ph.D. with a deep understanding of structural biology and general biochemistry
  • Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment.
  • Experience with other protein biochemical and/or biophysical characterization of protein complexes
  • Excellent presentation skills (written and oral) for effective team-based communication of results.
  • Experience with ubiquitin-proteasome system for protein degradation
  • At least 2 years of postdoctoral research experience in large macromolecular complex structure determination. Knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, structure determination and analysis
  • Skills in managing multiple projects and capability to prioritize.
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
The annual base salary range for this opportunity in the U.S. is $120,669-144,385.
In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
  • Flexible work models, including remote work arrangements, where possible
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Stock-based long-term incentives
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Apply now
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
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Salary Range
120,669.00 USD - 144,385.00 USD