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Company | Johnson & Johnson |
Address | San Diego Metropolitan Area, United States |
Employment type | FULL_TIME |
Salary | |
Category | Hospitals and Health Care |
Expires | 2023-08-11 |
Posted at | 10 months ago |
- Design, clone and produce mRNAs for optimal vaccine efficacy
- Develop and execute in vitro assays for the characterization of free and LNP formulated mRNA
- Design and execute experiments to characterize antigens and proteins encoded by mRNA candidates
- Ph.D. with 0-3 years in either a postdoc or industry, M.S. degree with 4-6 years in industry required
- Ability to communicate scientifically rigorous findings via verbal and written communications, visualizations, and presentations
- Effectively multi-task and advance various projects simultaneously and work collaboratively across teams in a matrix environment
- Design, plan, organize and execute complex experiments
- Up to 10% travel may be required
- Demonstrated lab work skills in several of the following: vector construction and DNA cloning, In Vitro Transcription (IVT), mammalian tissue culture, primary immune cell culture, gene expression using transduction, transfection, or electroporation, DNA/RNA isolation from mammalian cells, RT-qPCR setup and data analysis, flow cytometry, microscopy (ideally HTP), microplate-based assays including ELISA, luciferase, MSD, ELLA.
- Work independently
- Ability to contribute to project planning and goal setting, as well as identify and address technical challenges
- Expertise in vaccines, molecular biology, immunology, and/or closely related field
- Experienced in the design and production of plasmid DNA
- Hands on experience in design, modification, and optimization of mRNA
- Experience in characterizing in vitro/in vivo activity of mRNA or similar modalities
- Familiarity with mRNA and nanoparticle delivery systems
- A minimum of 2 years relevant pharmaceutical/biotech industry experience
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