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Stem Cell Transplantation Specialist, In Vivo

Company

Garuda Therapeutics

Address Cambridge, MA, United States
Employment type FULL_TIME
Salary
Category Biotechnology Research,Pharmaceutical Manufacturing
Expires 2023-06-04
Posted at 1 year ago
Job Description

Garuda Therapeutics is pioneering the development of off-the-shelf hematopoietic stem cell (HSC)-based cellular therapies for treating patients with blood, bone marrow, immune, and metabolic disorders. The company uses state-of-the-art technologies in developmental biology, gene-editing, stem cells, and mechanobiology to engineer safe, compatible HSCs in scalable quantities to transform the lives of patients in need of an HSC-transplant.


Garuda Therapeutics is seeking highly motivated research associate with outstanding expertise in mouse handling and procedures. Successful candidates will be integral in developing stem cell-derived therapies for hematologic disorders. The position requires enthusiasm, dedication, attention to detail, and teamwork ability. The position will be located in Cambridge, MA.



Key Responsibilities Include:

  • Perform in vivo imaging of luciferase-tagged cells
  • Perform retro-orbital and submandibular blood collection and sample preparation for FACS analyses
  • Perform intra-femoral, retro-orbital, and injections of hematopoietic stem cells in humanized murine models
  • Perform xenotransplantation to develop leukemia models
  • Perform bone marrow, spleen, and lymphnode extraction from murine models
  • Perform anesthesia via Isoflurane inhalation and or ketamine/ xylazine injection
  • Perform project-specific in vivo experiments
  • Perform subcutaneous and intraperitoneal injection of drugs/cells
  • Manage the mouse colonies
  • Collaborate with other team members to assist with project-specific- in vivo experiments


Required Qualifications:

  • Demonstrated excellence in planning and executing experiments
  • Highly self-motivated and flexibility in working schedule to accommodate weekend work if necessary
  • Independence and ability to troubleshoot
  • BS or MS with 5+ years of experience in animal procedures
  • Flexible team player excited to collaborate with internal and external partners
  • Attention to detail and careful record-keeping
  • Experience with hematopoietic stem cell transplant
  • Authorized to legally work in US
  • Ability to write technical reports and protocols
  • Excellent organizational skills and ability to manage multiple projects