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Senior Research Associate - Cell Biology
Company | Sanofi |
Address | South San Francisco, CA, United States |
Employment type | FULL_TIME |
Salary | |
Category | Chemical Manufacturing,Biotechnology Research,Pharmaceutical Manufacturing |
Expires | 2023-07-17 |
Posted at | 10 months ago |
Position Summary
Sanofi is discovering highly potent cancer therapies that are optimized for minimal side effects using our universal, protease-releasable masking technology (Pro-XTEN). Our discovery process utilizes innovative Protein Engineering and masking strategies to generate Conditionally-Activated Biologics. This is an opportunity to work with experts in Protein Engineering, Structural Modeling, LCMS analytics, bioconjugations, and bioinformatics. If you are highly motivated and capable of applying creative thinking and problem solving in a collaborative, fast-paced, and dynamic work environment then please send us your application.
We are seeking an experienced Senior Research Associate to join our Multidisciplinary Discovery Team. The successful candidate will have deep knowledge of cancer research and immunotherapy or proven expertise in recombinant protein expression from mammalian cells. The individual will design and conduct high quality experiments independently to support and advance therapeutic candidates from early discovery to IND-enabling studies. They will be responsible for data analysis and interpretation, thorough documentation of work, and clear communication of results in group settings.
Qualifications
Sanofi is leveraging our expertise in precision protein engineering to enable the promise of T cell engagers in solid tumors. Our goal is to improve the lives of people with cancer in pursuit of cures through the development and commercialization of breakthrough therapies that harness the immune system. We have designed XTEN, a validated therapeutic half-life extension technology. Our current focus is Pro-XTEN, a next-generation protease activated pro-drug platform, which enables selective activation of potent cancer therapies in the tumor microenvironment. This overcomes a common challenge facing potent immune system activators: on-target, off-tumor toxicity. Sanofi's lead programs employ the Pro-XTEN technology to enhance the safety profile of T cell engagers. XPATs (XTENylated Protease-Activated T Cell Engagers) have the potential to make off-the-shelf therapies redirecting T cells to solid tumors a reality.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
The salary range for this position is $68,145.00 - 90,860.00 to $113,575.00. All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the link, www.benefits.sanofiusallwell.com
#GD-SA
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
Sanofi is discovering highly potent cancer therapies that are optimized for minimal side effects using our universal, protease-releasable masking technology (Pro-XTEN). Our discovery process utilizes innovative Protein Engineering and masking strategies to generate Conditionally-Activated Biologics. This is an opportunity to work with experts in Protein Engineering, Structural Modeling, LCMS analytics, bioconjugations, and bioinformatics. If you are highly motivated and capable of applying creative thinking and problem solving in a collaborative, fast-paced, and dynamic work environment then please send us your application.
We are seeking an experienced Senior Research Associate to join our Multidisciplinary Discovery Team. The successful candidate will have deep knowledge of cancer research and immunotherapy or proven expertise in recombinant protein expression from mammalian cells. The individual will design and conduct high quality experiments independently to support and advance therapeutic candidates from early discovery to IND-enabling studies. They will be responsible for data analysis and interpretation, thorough documentation of work, and clear communication of results in group settings.
Qualifications
- A minimum of a Bachelor's degree in a scientific discipline with 3+ years of work experience or a Master’s degree with 1+ years of work experience. Equivalent experience may be accepted.
- Prior experience working with T cell engagers and/or cytokines is highly desired
- Strong background in immunology and experience working in immune oncology is preferred
- Experience in Immunology, Immune Oncology research or Biology.
- Experience in the Biotech/Pharma industry preferred
- Proven expertise with in vitro immunology laboratory techniques that include cell isolation, FACS, cytokine analysis, cytotoxicity assays, and proliferation assays is desired
- Proficiency with software such as Geneious, GraphPad Prism, SoftmaxPro etc.
Sanofi is leveraging our expertise in precision protein engineering to enable the promise of T cell engagers in solid tumors. Our goal is to improve the lives of people with cancer in pursuit of cures through the development and commercialization of breakthrough therapies that harness the immune system. We have designed XTEN, a validated therapeutic half-life extension technology. Our current focus is Pro-XTEN, a next-generation protease activated pro-drug platform, which enables selective activation of potent cancer therapies in the tumor microenvironment. This overcomes a common challenge facing potent immune system activators: on-target, off-tumor toxicity. Sanofi's lead programs employ the Pro-XTEN technology to enhance the safety profile of T cell engagers. XPATs (XTENylated Protease-Activated T Cell Engagers) have the potential to make off-the-shelf therapies redirecting T cells to solid tumors a reality.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
The salary range for this position is $68,145.00 - 90,860.00 to $113,575.00. All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the link, www.benefits.sanofiusallwell.com
#GD-SA
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
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