Senior Scientist - Ipp Structural Biology
By Amgen At , Thousand Oaks, Ca $120,669 - $144,385 a year
Master’s degree and 4 years of structural biology and general biochemistry experience or
Bachelor’s degree and 6 years of structural biology and general biochemistry experience
Experience with ubiquitin-proteasome system for protein degradation
Excellent presentation skills (written and oral) for effective team-based communication of results.
Skills in managing multiple projects and capability to prioritize.
Experience with other protein biochemical and/or biophysical characterization of protein complexes
Scientist, Replicon Molecular Biology
By Johnson & Johnson At , San Diego $102,000 - $163,500 a year
Experienced in the design and production of plasmid DNA
Hands on experience in design, modification, and optimization of mRNA
Experience in characterizing in vitro/in vivo activity of mRNA or similar modalities
A minimum of 2 years relevant pharmaceutical/biotech industry experience
Design, clone and produce mRNAs for optimal vaccine efficacy
Develop and execute in vitro assays for the characterization of free and LNP formulated mRNA
Molecular Biology Scientist (Must Molecular Biology Lab Work Exp Required)
By WFYI Public Media At San Jose, CA, United States
General knowledge of molecular biology, biochemistry, or a related discipline.
NGS based assay experience preferred.
Effective oral and written communication skills.
Minimum 3 years of relevant experience
Molecular biology lab work experience required
Next-Generation Sequencing (NGS) experience preferred
Scientist/ Sr. Scientist (Islet Biology), Biology
By Biomea Fusion At San Carlos, CA, United States

Scientist with hands on experience in isolating, culturing and handling experiments with human islets. Molecular biology and Cell biology skill sets. Experience in drug discovery setting.

Scientist I, Translational Biology
By Escient Pharmaceuticals At San Diego, CA, United States
Computer Skills: Advanced knowledge of Excel, Word, PowerPoint and Graphpad prism
Proficient in laboratory bench skills such as ELISAs, Western blots, qPCR, Flow cytometry, and/or histology
Effective troubleshooting and problem-solving skills
Experience with in vitro cell culture including primary cell lines, immune cells, neurons, transformed cell lines, and ex-vivo explants
Experience in basic rodent handling, dosing, in vivo and ex vivo efficacy measures
Experience with in vivo animal inflammation and autoimmune disease model development and animal handling is a plus
Scientist, Replicon Molecular Biology
By Johnson & Johnson At San Diego Metropolitan Area, United States
Experienced in the design and production of plasmid DNA
Hands on experience in design, modification, and optimization of mRNA
Experience in characterizing in vitro/in vivo activity of mRNA or similar modalities
A minimum of 2 years relevant pharmaceutical/biotech industry experience
Design, clone and produce mRNAs for optimal vaccine efficacy
Develop and execute in vitro assays for the characterization of free and LNP formulated mRNA
Scientist, Rna Biology Jobs
By Switch Therapeutics At South San Francisco, CA, United States
The candidate should have strong interest and skills in management, training, and mentoring.
Excellent communications, organization, and time management skills.
Projects will require considerable technical skill and innovation.
One to five years of experience in post-graduate research (experience will determine position level).
Research activities will cover a mix of foundational scientific questions and novel applications.
The candidate will need to work collaboratively across the company to build support for research objectives and communicate important outcomes.
Sr. Scientist, Systems Biology
By Ionis Pharmaceuticals, Inc. At Carlsbad, CA, United States
Strong oral and written communication skills
Develop computational methods for integrative analysis of multi-omic datasets
Apply machine learning and statistical analysis to predict drug action
Design and develop pipelines to address novel analytical challenges and to automate established analysis in a cloud computing environment
Organize and document analysis strategies
Work in cross-disciplinary teams and communicate findings to broad audience of biologists, chemists and statisticians
Scientist/Senior Scientist, Molecular And Cell Biology
By Altos Labs At San Francisco, CA, United States
Support and manage internal/external collaborations in one or more multidisciplinary projects to accelerate essential research activities
Engage in ground-breaking and innovative science
Study the mechanistic basis of cell and organismal resilience for health and rejuvenation
Develop project-specific experimental strategies, techniques, and procedures
Assist PI with training lab members, including scientists and technicians
Contribute to writing and dissemination of research results
Computational Biology Data Scientist, Cancer Biology
By insitro At South San Francisco, CA, United States
Deep knowledge in one or more areas of cancer biology gained through research, and familiarity with other hallmarks of oncogenesis
Extensive experience with scientific programming in Python and R, including expertise using numpy, scipy, bioconductor, and similar toolkits
Experience with transcriptomics (e.g., scRNA-seq) and/or imaging (e.g. digital histopathology)
Experience with spatial transcriptomics and/or proteomics
Experience working with diverse functional genomic assays (RNA/DNase/ATAC/ChIP-seq, etc)
Experience working with clinicians or wet lab biologists to evaluate and follow-up on computational findings
Scientist 1, Platform Biology Jobs
By BioSpace At Hayward, CA, United States
PhD or equivalent experience in Genetics, Genomics, Systems Biology, Computational Biology
Experience using and refining quantitative microscopy methods to derive new biological insights
Keen analytical and problem-solving skills. Familiarity with Python, R, or other programming languages encouraged
Strong communication skills and proven ability to build open and collaborative relationships within and across teams
Mental health and wellness benefits
Mentor junior research associates to conduct laboratory experiments. Keep detailed and organized records of experimental protocols and results
Molecular Biology Scientist Jobs
By ATUM At Newark, CA, United States
Critical thinking skills in experimental design and data interpretation
Excellent people, communication, and organizational skills
Experience with automation is a plus.
Excellent benefits package, including employer-paid medical and dental insurance, 401(k) plan with employer matching, commuter benefits
PCR and nonstandard PCR methods
Methods for DNA design, assembly, and cloning.
Scientist/Sr. Scientist, Biology
By BioSpace At San Diego, CA, United States
Hands-on experience on in vitro cellular assay development, IHC, FACS, et al, histology knowledge is preferred.
Efficiently manage and maintain laboratory equipment and tools.
Working experience on in vivo animal models, drug PK and PD evaluation is preferred.
Excellent communication and technical writing skills.
Work closely with a multidisciplinary team.
Analyze and communicate results during department/project meetings.
Principal Scientist, Neuroscience Biology
By BioSpace At San Diego, CA, United States
Establishes project direction integrating science, key technical knowledge, and program objectives
PhD degree in Neuroscience with post doc experience; At least 10 years of experience in drug discovery process
Extensive knowledge in neuroscience, immunology, and neuroimmune interactions
Multiple years of industry experience in drug discovery from target identification, validation, portfolio entry, to NME nomination
Experience in building external connections with academic labs and CROs
Independently designs and implements extensive scientific research projects.
Scientist Ii, Neuroscience Biology
By BioSpace At San Diego, CA, United States
PhD degree in Neuroscience with post doc experience
Experience in 2D and 3D cell cultures for drug screening and drug validation
Contributes to design, development and execution of research assignments, potentially contributing to multiple projects
Delivers data to project teams as required
Prosecutes in vitro biology experiments as designed and outlined by Supervisor
Initiates investigation of new experimental approaches to a wide range of problems using scientific theory and technical literature
Associate Scientist, Biology (Ocular)
By Arrowhead Pharmaceuticals At San Diego, CA, United States
BS or MS with 2+ years of experience in cell biology, molecular biology, immunology, pharmacology or a related field of biology
Experience in standard cellular and molecular biology techniques (Cell culture, ELISA, Cell-based assays, Immunofluorescence, Western blotting, Microscopy, RNA/DNA isolation, qPCR)
Excellent oral and written communication skills
Experience/exposure in rodent animal models (mouse or rat is fine)
Previous experience with ocular related projects is a plus
Design and conduct/execute in vitro, ex vivo and/or in vivo studies to facilitate drug discovery and development in various disease areas
Scientist Ii, In Vivo Biology / Pharmacology
By Vividion Therapeutics. Inc. At San Diego, CA, United States
Cross-departmental coordination and project management experience required
Ph.D. with 0-4 years industry experience in biology, pharmacology, physiology, or related discipline (e.g., DVM) in a biotech/industrial setting
Experience ensuring quality control and accurate analysis of data provided by CROs
Experience with oncology models is required
Experience in planning and conducting in vivo IND-enabling studies is preferred
Excellent interpersonal skills, with the ability to interact professionally and effectively in a dynamic, multi-disciplinary, and highly collaborative team environment
Scientist 1, Cell Biology For Neuroscience Research
By BioSpace At San Rafael, CA, United States
Use patient-derived disease models to predict pharmacodynamic requirements for efficacy
Cross-team collaboration and engagement, data analysis and organizational skills
Excellent written and verbal communication skills
At least 0-2 years of relevant postdoctoral or industry research experience with a track record of productivity
Establish in vitro screening platforms and disease models for neurological indications
Assist in the development of cellular screening platforms for lead identification and optimization
Scientist, In Vitro Biology
By aTyr Pharma At , San Diego, 92121, Ca $100,000 - $130,000 a year
PhD degree in biochemistry/biological sciences or a related discipline with 0-3 years of postgraduate experience
Extensive experience with culture of mammalian cells and cell-based assays
Strong analytical skills and problem solving ability
Strong verbal and written communication skills
Strong background in cell biology, including cell signaling
Training in fibrosis and fibrotic disease models is highly desired
Molecular & Cell Biology Research Scientist (Lung Biology)
By Vertex Pharmaceuticals At , San Diego, 92121, Ca $97,760 - $146,640 a year
Manage project timeline and coordinate cross-departmental efforts as necessary.
Bachelors Degree (or equivalent degree) in molecular biology, cell biology, biochemistry, or related disciplines and 6+ years of relevant employment experience
Must have work experience in lung biology
Experience in primary cell culture, particularly lung epithelial cells (HBE or AT2 cells)
Experience with cell-based assay development and/or validation
Excellent communication and presentation skills