Research Senior Associate Jobs in San Diego, San Diego, California

Education, Experience and Skills Requirements

Excellent organizational and lab management skills

Experience with bacterial growth and manipulations for cloning

Experience in using Geneious (or other DNA sequence programs)

Other preferred experience (but not required). Let us know if you have worked hands on with:

BS or MS in biochemistry or related fields

Extensive experience in tissue culture and aseptic techniques

Experience in tissue processing, cell isolation and enrichment

Strong computer skills, including GraphPad Prism, FlowJo, and MS Word, Excel, and PowerPoint

Excellent communication and organizational skills

Design, conduct, and analyze experiments using methods including, but not limited to western blotting, flow cytometry and cell cytotoxicity assays

Develop analytical assays to support pharmacological characterization of new drug candidates

·B.S. with 0-2 years of relevant experience in scientific discipline.

·Outstanding communication and interpersonal skills across the primary team and all company functions are essential.

·Proven organizational and planning skills with extreme attention to detail and troubleshooting and ability to multitask.

·Experience with Microsoft suite (Word/Excel/PowerPoint) and team communication software preferred.

·Biochemical assays, tissue culture and/or cell assay experience is highly preferred.

·Collect and analyze experimental data utilizing software templates for computer assisted data analysis.

Bachelor's degree with 3+ years of industry experience

Must have experience with mammalian cell culturing experience

Experience with cell transfection is a big plus

Some molecular biology knowledge is a plus

Perform all other duties as assigned by supervisor or manager.

At least 1 year of mammalian cell culture experience (suspension or adherent) after undergrad.

Strong work ethic, communication skills and goal-oriented personality.

Demonstrable experience keeping pristine records of experiments and DNA constructs produced using a digital laboratory notebook.

Strong problem-solving and critical thinking skills.

Experience with suspension cell culture.

B.S. or M.S. in relevant discipline with 3-7 years of industry experience (neuroscience or metabolic background is preferred)

Experience developing and executing rodent disease model studies (IACUC submission, study design and execution, data analysis and presentation, data archiving)

Familiarity with or direct animal behavioral experience including motor function, spatial learning and memory, and anxiety

Experience with multiple methods of tissue culture, processing, and analytical analysis (flow cytometry, ELISA, Immunoblotting, qPCR, Immunofluorescence)

Key Responsibilities and Job Functions

Systemic biomarker collection and analysis, including cardiometabolic, renal and hepatic function

Experience with developing/writing SOPs, documenting and tracking lot numbers and using lab management systems

1-5+ years experience in core facility, industrial molecular or microbiological role

Experience with maintaining cell cultures

Experience with DNA and RNA extraction, qPCR; familiarity with NGS

Experience with classical microbiology techniques

Experience working closely with Scientists and Computational Biologists to design, develop and optimize assays

Demonstrated knowledge of Molecular Biology techniques including nucleic acid extractions and PCR.

Strong analytical skills including the ability to problem solve and troubleshoot experimental processes and provide analysis.

Strong oral and written communication skills including the ability to organize and share analysis reports.

Demonstrated interpersonal skills including the ability to work autonomously and as part of a diverse collaborative team.

Perform cell culture and cell line maintenance.

Perform complex experimental procedures to support DNA/RNA isolation and QC.

B.S./M.S. in Chemistry, Biochemistry, Food Science, or similar field with 1+ year of product innovation experience or analytical lab experience

Experience with GCMS (TOF, single quad, FID)

Experience with analytical methods of sample preparation for analysis

Strong chemical intuition and knowledge of flavor chemistry

Experience in designing experiments, data analysis, data interpretation, and communication results to fellow researchers

Experience with innovative research and development projects

Experience working on Clinical Trial Research and Clinical Research Trial Documentation

Previous experience within the Medical Device or Pharma industry

5+ years’ experience in Clinical Research

Comfortable working with a lot of documentation

Bachelor’s Degree – Any life sciences related degree

Proven experience with assays, such as PCR, ELISA, and /or mammalian cell culture.

Positive, professional self-starter with a passion for science, innovative technical and analytical skills required to perform at the highest level

Excellent clear and concise writing skills for technical reports and documents along with strong verbal communication skills

Experience in analytical method development and assay transfer

Be BOLD (Find a Way)

Care Deeply – for our patients, each other and our work

BS/MS degree in chemistry, pharmaceutical science, or related scientific discipline with 3+ years of relevant experience

Hands-on experience in method development and quantitative analysis of small molecule using LC-MS/MS instruments is highly desirable

Experience with in vitro ADME assays

Working knowledge of Phoenix WinNonLin software for PK analysis is a plus

Excellent communication and writing skills

Conduct LC-MS/MS method development to support drug/metabolites and biomarker analysis

Highly motivated with excellent attention to detail. Good communication (oral and written) and collaboration skills.

Experience in cell culture and tissue preparation techniques.

Experience in troubleshooting and optimization of molecular biology assays including reagent formulation and workflow optimization.

Experience in product development including product release.

Advanced fluorescence imaging techniques. Experience in microscopy image analysis.

Additional Desirable Skills To Have

Education, Experience And Skills Requirements

Any suitable combination of education, training, or experience is acceptable.

Evaluate new technologies and methodologies to support and advance analytical capabilities on the therapeutic products.

Handle and troubleshoot instrument issues such as on DNA sequencers and qPCR instruments.

Represent as subject matter expert on analytical molecular assays to support Chemistry, Manufacturing and Controls (CMC) team on new pharmaceutical products.

Supervise 2 Research Associate Contractors.

A Manager with broad experience, passionate about the science, with an extensive research and development portfolio

Perform routine and novel testing to support biological therapeutic products from early-stage development through late-stage/commercialization and their lifecycle management.

A team with broad experience and passion for science

Excellent verbal and written communications skills

Experience troubleshooting and developing analytical methods.

Experience in analytical method troubleshooting, optimization, and validation.

Manage and organize assay workflows, draft protocols, and support lab operations

Experienced in ELISA, imaging and molecular and microbiology techniques

An efficient working knowledge of scientific software programs such as Graphpad Prism, FLowJo and image analysis tools

Demonstrated experience designing high throughput sample pipelines and ability to implement protocols and pipelines into lab workflow

Experience in Chromatography (GC, HPLC) and Flow Cytometry including proper sample preparation

Independently execute biochemical and molecular biology experiments and use in-house software tools to analyze data.

Experience in Immunology, Immune Oncology research or Biology.

Experience in the Biotech/Pharma industry preferred

Strong background in immunology and experience working in immune oncology is preferred

Prior experience working with T cell engagers and/or cytokines is highly desired

Proficiency with software such as Geneious, GraphPad Prism, SoftmaxPro etc.

This position is eligible for LBNL’s Employee Referral Program benefit(s).

Lawrence Berkeley National Laboratory has multiple openings for a Senior Research Associate in Berkeley, CA.

Equal Opportunity and IDEA Information Links:

Advanced site monitoring; study site management; and registry administration skills.

Substantial site management experience or equivalent experience in clinical research, with an understanding of clinical trials methodology and terminology.

Manage vendors to ensure timely and quality deliverables. Develop trackers for sample management.

Comfortable working with different levels of the company including senior level management.

Participate in preparation of vendor requirements and project scope and selection of study vendors.

Manage recruitment and enrollment metrics, provide weekly study updates and slides for Clinical Development.

Experience with gene therapy or small molecules is not a requirement but is considered a positive.

Knowledge in standard molecular biology and biochemistry techniques (i.e., RNA, DNA, protein extraction, western blotting, qPCR, IHC, etc.…).

Execute ex vivo experiment and analyses to support in vivo study conclusions or as independent studies.

Maintaining detailed records of experimental protocols and data in accordance with company policy.

Present findings in both small and large group company meetings.

Managing multiple tasks efficiently, communicating clearly and effectively, and building open and collaborative relationships are essential.

We are an Equal Opportunity Employer offering a competitive salary and benefits.

Experience deploying fluorescence microscopy, immunohistochemistry and RNA in situ hybridization in primary cells and tissue sections is preferred.

The ability to manage multiple tasks efficiently, work independently, to communicate effectively, and attention to detail is critical

Collaborate on multiple projects simultaneously and work as part of a cross-functional team.

Analyze and interpret data, present findings in group presentations.

Preparation of technical reports, summaries and detailed protocols, and contribute to company reports as requested.

Experience with gene therapy or small molecules is not a requirement but is considered a positive.

Knowledge in standard molecular biology and biochemistry techniques (i.e., RNA, DNA, protein extraction, western blotting, qPCR, IHC, etc.…).

Execute ex vivo experiment and analyses to support in vivo study conclusions or as independent studies.

Maintaining detailed records of experimental protocols and data in accordance with company policy.

Present findings in both small and large group company meetings.

Managing multiple tasks efficiently, communicating clearly and effectively, and building open and collaborative relationships are essential.