Research Associate I/Ii Or Senior Research Associate I

Tenaya Therapeutics is a publicly held biotechnology company committed to a bold mission: to discover, design, develop and deliver curative therapies that address the underlying drivers of heart disease. Founded by leading cardiovascular scientists from Gladstone Institutes and University of Texas Southwestern Medical Center (UTSW), we are advancing a deep and diverse pipeline that includes both gene therapies and small molecules.

Tenaya is headquartered in South San Francisco, California, USA, with a team that comprises over 140 employees. Inspired by the majesty of Tenaya Peak in Yosemite National Park, our name represents the tenacity of our team in reaching our ultimate peak – the delivery of new therapies for heart disease to the patients who need them.

For more information, please visitwww.TenayaTherapeutics.comand follow us on LinkedIn.

Diversity & Inclusion is a core Value for Tenaya Therapeutics, and we encourage those from under-represented communities to apply.

Tenaya has an immediate need for a Research Associate I to Senior Research Associate I to support the Pharmacology team. The ideal candidate is a self-starter and problem-solver who will work closely with the team to drive the company’s future success. Ideally, you thrive in a fast-paced environment where every day is unique. You are confident, poised and cool-headed, no matter how much is changing around you. You strive for excellence in every facet of your work, and you understand the excitement and commitment of pharmacology roles. Finally, you love being part of a team aligned around a compelling mission.

Responsibilities

• Participate in cross-functional collaborations, interdisciplinary project team activities; establish and maintain excellent working relationships with collaborative partners throughout the company and CROs
• Maintaining detailed records of experimental protocols and data in accordance with company policy.
• Present findings in both small and large group company meetings.
• Perform routine hands-on work for in vivo experiments and data analysis of efficacy, PK/PD, biodistribution, and safety studies, driving comprehensive and highly integrated profiling of Tenaya drug candidates.
• Participate in scheduling, execution, documentation and analysis of data generated from in vivo animal studies with supervision. Generate study reports for completed in vivo studies with supervision.
• Execute ex vivo experiment and analyses to support in vivo study conclusions or as independent studies.

Qualifications

• Knowledge in standard molecular biology and biochemistry techniques (i.e., RNA, DNA, protein extraction, western blotting, qPCR, IHC, etc.…).
• B.S. or M.S. in pharmacology, biology, physiology, bioengineering or related discipline, prefer to have > 1 year of laboratory experience in industry or academic lab.
• Experience with gene therapy or small molecules is not a requirement but is considered a positive.
• Any experience within vivocardiovascular techniques, such as rodent handling, animal surgery, ECG recording, tail cuff blood pressure measurement, tail vein or eye bleeding, GTT, dosing (IV, IP, PO, SC) is a plus. Echocardiography is a particularly valued skillset.
• Managing multiple tasks efficiently, communicating clearly and effectively, and building open and collaborative relationships are essential.
• A positive attitude and strong attention to detail are required.
• Ability and willingness to work with small rodent animals are an absolute requirement, particularly the ability to perform necropsy to collect tissues forex vivoexperiments and tissue sectioning.

This position is flexible from Junior RA to senior RA depends on qualification. Tenaya considers a wide range of factors when determining compensation, including but not limited to skill sets, experience, interview performance, and organizational needs.