Senior Manufacturing Associate-Downstream Jobs

We are a dedicated group of scientists, physicians, and businesspeople working together toward one goal: to discover and develop therapies that can unleash the power of the body’s immune system to treat and potentially cure cancer. We are passionate about the work we do every day at Agenus to deliver on the promise of immuno-oncology. If you’re looking for an inspired environment, passionate colleagues, and a culture that nurtures learning, innovation and team success, we invite you to join us.

The Senior Manufacturing Associate will have the opportunity to coordinate and collaborate with other cross-functional departments, including Quality, Facilities, Procurement, etc. This position requires independent execution of quality systems (includes initiation of critical work orders, change requests, deviations, corrective action preventative action (CAPA)). There will be times when work schedules change to accommodate the processing schedule. Contribution and participation will be required for additional assignments and projects including report writing, data analysis, experiment/validation execution, data compilation/summarization, etc. The Senior Manufacturing Associate will assist with planning and scheduling of the upstream/downstream operations. The Senior Manufacturing Associate will have more engagement and responsibility for continuous process improvement.

Roles And Responsibilities

• Identify and implement equipment and process improvements.
• Execute quality systems (including critical work orders, change requests, engineering change, deviations, corrective action preventative action (CAPA)).
• Record and document procedures with detail and accuracy. This includes batch records, training records, logbooks, standard operating procedures (SOPs) and validation protocols.
• Monitor fermentation and purification operations (including trouble shooting and diagnosis of instruments, equipment, process, etc.)
• Assist CMC team with technical transfer activities.
• Sample solutions and perform analytical assays (including cell counts, pH, conductivity, etc.)
• Assist in development and creation of the upstream/downstream process.
• Create and revise standard operating procedures, batch records, specifications, etc.
• Weigh and prepare culture media, buffers, and solutions.
• Set-up, prepare, and operate manufacturing equipment/labware/assemblies (includes filtration skid, chromatography skid, fermenter, autoclave/sterilizer, bench top meters (pH/conductivity/osmometer), etc.) in accordance with current good manufacturing practices (cGMP).
• Coordination and collaboration of activities with other departments, and with vendors
• Plant cleaning (including floors, benches, bioreactors, equipment, etc.) waste disposal, lean manufacturing and good manufacturing practices (GMP)/compliance.
• Perform technical training (including hands-on and class-based training)
• Assist in the creation of the Bill of Materials for the upstream/downstream process.

Requirements

• Knowledge of upstream equipment (laminar air flow hood, shake flask scale-up, single use bioreactors and control software, and analytical instruments for cell count, osmolality, and metabolites) are essential for this position.
• Teamwork and communication are key attributes needed for this position, as this role will be part of a small team within manufacturing. A collaborative attitude and a positive work ethic are key traits for success.
• Attention to detail and accuracy for record keeping and documentation is mandatory in this position
• Knowledge of downstream equipment (columns, skids, flow/UV/pH/conductivity/etc. sensors), filtration equipment, solution preparation equipment (laminar air flow hood, agitator mixers, bench top meters) are essential for this position.

Education Requirements

• 2 years of college science in Cell Biology, Biochemistry, Chemistry, Biology, with 2 to 4 years of related experience
• Or 4 to 8 years of experience and/or training, or equivalent combination of education and experience.

Agenus is Delighted to Provide you With a Comprehensive Benefits Plan, Including Some of the Following:

• Catered Lunch
• Free Parking
• Education Assistance Program
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Employee Stock Purchase Plans
• Flexible Vacation Plan-In a time when we move at the speed of light, what matters most is what we achieve, not how many hours we clock or accrue. We want people to take breaks when they need them most and own their time. Our philosophy at Agenus is that freedom to take this time will lead to clarity, creativity and innovation through rested and refreshed eyes. With our Flexible Vacation Plan, Agenus will not limit the amount of vacation you can take. It will allow you to take the vacation time as you need, while fulfilling your job responsibilities and making meaningful contributions to our mission
• Highly competitive and inclusive medical, dental and vision coverage options
• 401k match and Financial Planning tools
• Employee Assistance Program
• Care.com Memberships

Our core values

The way we work sets Agenus apart.

We put the patient first

We aspire to change the world, improving the experience and options available for every single cancer patient. The answers are out there, and patients are waiting.

We are bold, and we are one

We believe that the only way to deliver on our goals is to aim high and work as one global team. We look for opportunities to challenge, collaborate with, and support one another. We aim to break conventional standards and perform at extraordinary levels.

We work with integrity, respect and honesty

These three building blocks serve as pillars for how we behave, operate, and execute our mission.

We are a culture of ownership and accountability

We hold ourselves accountable not only for exceptional results, but how we get our results.

We are obsessively curious and deeply committed to learning

We live in a fast-paced environment that requires us to learn at or above the speed of change. We believe that curiosity fuels the desire to create, and learning provides the tools to progress.

We perform at our best every day

Every day counts. We confront insurmountable obstacles, problems and choices with intellect, perseverance and hard work.