#123230 Hosp LabTech II, Manufacturing Associate

DESCRIPTION

The Advanced Cell Therapy Laboratory (ACTL) offers expert assistance and hands-on services to investigators who require cGLP/cGMP systems and facilities. We aid in the transition from research and development to compliant and clinically-relevant manufacture of cell therapy products for IND-enabling studies or Phase I/II trials.We provide assistance with cell banking, process scale-up, product characterization, document writing, product stability assessment, and packaging.

Under general supervision, responsible for performing GMP (Good Manufacturing Practice) cell culture and the associated assays within a laboratory or clean room. Perform a broad range of laboratory activities in the support of cell therapy products under cGMP for use in pre-clinical & clinical studies. Undertakes translational research and development and validation studies of processes and equipment as required. Performs all associated CTL procedures that are required to ensure the daily operation of the CTL and to maintain CTL licensing and accreditation, as indicated. Responsible for participating in the quality management and accreditation process. Responsible for culturing T cells, NK cells, neuronal cells, stem cells, embryonic stem cells, and other cell types derived from donors.

MINIMUM QUALIFICATIONS

• Bachelors degree in a science related field of study and one year of relevant experience or a combination of experience and education required.
• Willingness to adhere to established UCSD guidelines for safety and environmental issues.
• Demonstrated experience with aseptic cell culture methods, including cryopreserving, thawing, and expanding cell lines, is required.
• Demonstrated ability to work with a variety of individuals including faculty, clinicians, and staff and to work as a team member in a support position.
• Hands-on experience in a pharmaceutical, biotech, drug manufacturing, or academic environment is required, with knowledge of clean room practices being essential.
• Ability to follow detailed instructions described in SOPs and batch records and to record data accurately and in a legible manner per cGMP requirements.
• Strong organizational skills with ability to prioritize tasks and to work under the pressure of multiple demands.
• Willingness to work in environment where biological (including infectious agents and blood borne pathogens), chemical, and radiological hazards are present, to perform research on the human pluripotent stem cell, to work with viruses that are infectious to humans, including adeno-associated viruses, Sendai viruses, and lentiviral vectors which are derived from human immunodeficiency virus (HIV).
• Experience using basic laboratory equipment; knowledge of safe laboratory procedures.
• Strong computer skills using MS Word, Excel and email.

PREFERRED QUALIFICATIONS

• Experience and knowledge in iPSC cell culture techniques, including culturing and maintenance.
• Familiarity with the Miltenyi CliniMACs device, flow cytometry, and PCR techniques.

SPECIAL CONDITIONS

• Willingness to work with embryonic stem cells, work with viruses that are infectious to humans, including adeno-associated viruses, Sendai viruses, and lentiviral vectors which are derived from human immunodeficiency virus (HIV).
• Willingness to work in BioSafety Level II environment where biological (including infectious agents and blood borne pathogens) hazards are present.
• Must be able to work various hours and locations based on business needs including occasional weekends.

Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).
If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.

UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community.

UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html

UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.

UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening.