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Scientist, Platform Biology Jobs
Company | Flagship Pioneering |
Address | Cambridge, MA, United States |
Employment type | FULL_TIME |
Salary | |
Category | Research Services,Biotechnology Research |
Expires | 2023-09-21 |
Posted at | 9 months ago |
What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?
- Drive biology experiments to assess targets, biochemically evaluate candidate small molecules, and support drug discovery of several high value, unprecedented targets
- Work collaboratively in cross-functional chemistry, proteomics, drug discovery and AI/machine learning teams
- Develop & implement a high throughput platform for the characterization of induced protein interactions using diverse chemical and molecular biology techniques such as unnatural amino acid encoding, site-directed mutagenesis, and activity-based protein profiling.
- Ensure rapid and accurate turnaround of data, to agreed timelines, to drive achievement of key project goals
- Translate experimental data into meaningful insights, and present the analyzed data in team meetings
- Build chemical biology & molecular biology platform to invent, create and validate novel chemistry modalities, including induced proximity technologies, through key proof of concept studies
- Excellent communication and presentation skills, capable of conveying scientific information in a concise and effective manner.
- Demonstrated ability to work within highly skilled teams in a fast-paced, quickly evolving technical environment.
- Experience with mammalian cell culture, transfection techniques, and cell-based reporter assays is required.
- Sound knowledge of other disciplines involved in drug discovery (biophysical methods, NGS, HT screening, LC-MS).
- Expertise in modern molecular biology techniques including the development of methods to site-specifically incorporate unnatural amino acids into proteins is a plus.
- Experience developing and implementing high-throughput cell-based assays using automated liquid handling techniques is a plus.
- Experience working with induced proximity technologies, such as PROTACs and molecular glues, is preferred.
- Ph.D. in Chemical Biology, Biochemistry, Molecular Biology or equivalent with 0-2+ years of experience in an industry or postdoc position.
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