Protein Scientist Ii Jobs in Los Angeles, California

Excellent oral (including public speaking) and written communication skills

Experience building and/or working in collaborative, diverse and inclusive team environments

Strong interpersonal skills, demonstrated through mentorship, listening and good communication

The following qualifications are required:

Develop and/or refine existing open-source aquatic algorithms for SBG, and lead their validation

Lead SBG DEIA collaborations and activities with minority and underrepresented groups

PhD in chemistry, chemical engineering, or a related field or MS +3 years of experience

Demonstrated experience with the design and synthesis of complex novel targets

Relevant laboratory experience in life science applications.

Experience executing molecular biology assays.

Experience in surface chemistry, polymer chemistry, bioconjugation and surface functionalization.

Experience with imaging of biological samples

iota offers a very competitive benefits package that includes the following:

Maintains in-depth scientific knowledge in relevant therapeutic areas

Bachelor's degree with 2+ years research experience in biology, oncology, or immunology

Experience with molecular and/or cell-based assays or histopathology

Experience in independently optimizing experimental methods and assays

Experience working in interdisciplinary environments and building relationships with key external partners

Wellness, caregiver and ergonomics, mental health and education benefits

1+ years of hands-on experience designing and analyzing CRISPR gene editing or epigenetic editing experiments in mammalian cells

1+ years hands-on experience in three of the following areas:

1+ years experience developing novel CRISPR tools for gene and epigenetic editing

1+ years experience developing novel assays in human cells for high throughput tool evaluation

1+ years experience working with disease-relevant human cell lines and primary cells

Excellent verbal, presentation and written communication skills are essential and capacity to effectively work in a team environment

Experience working with internal and external teams in a collaborative environment to deliver on goals and deadlines

Outstanding problem-solving and data analysis skill and ability to independently record scientific progress and maintain detailed laboratory notebook

Previous industry experience in Biotech or Pharmaceuticals

Experience reviewing the proper operation and maintenance of current laboratory equipment and analytical instruments

M.S. with minimum of 2-4 years or B.S./B.A. with 3-5 years Biotech or Pharmaceuticals industry experience preferred

Effectively analyze and interpret data, as well as communicate updates to management and cross-functional teams

Minimum of 4+ years of research experience, 0-2 years of related experience post-PhD

Proven expertise in protein purification techniques, with working knowledge of FPLC platforms (AKTA, Bio-Rad).

Experience with prokaryotic and eukaryotic expression vectors and construct design for structural biology studies.

Attention to detail, accurate record keeping, and strong oral and written communication skills

Prior experience with protein purification and protein characterization of membrane-spanning proteins such as GPCRs, is a bonus.

Literature review and investigation to identify key requirements on structure-based computational design for specific GPCR binding antibodies.

Great communication skills, (oral and written), along with a proven record of presentations and publications.

Experienced in research of GPCRs family would be highly desirable.

Hands-on experience in wet-lab techniques, coupled with a willingness to undertake training for additional wet-lab support tasks.

Experienced in molecular dynamics, simulation, physics-based computations or similar. (In particular of Rosetta).

Exceptional collaborative skills are a crucial, as the role requires working closely with a multi-functional team.

Minimum Qualifications – Education And Experience

Preferred Qualifications – Education And Experience

Maintain laboratory equipment and manage supplies

Other projects or responsibilities as may be required

Biotech industry experience or research experience

Good analytical and communication skill

Minimum Qualifications – Education And Experience

Preferred Qualifications – Education And Experience

Other projects or responsibilities as may be required.

M.S. with generally more than 8 yrs of relevant working experiences.

Ph.D. with generally 2-4 years of post-doctoral training or relevant working experiences

Experience in process development and optimization for stem cells and/or hybridoma cell culture

Bachelor's Degree in Biochemistry, Bioengineering, Molecular Biology, or related fields and 5+ years of academic / industry experience

OR Master's Degree in Biochemistry, Bioengineering, Molecular Biology, or related fields and 3+ years of academic / industry experience

OR PhD No experience required

Experience and enthusiasm to work with mRNA and yeast display

In-depth understanding and experience in antibody engineering is highly desirable

Demonstrated experience in working in a cross-functional organization is required

Manage and maintain mammalian suspension and adherent cell lines and perform aseptic techniques as needed

One to two years relevant experience in an academic lab (classes not included) or biotechnology work experience is required

Organized and detail oriented, possessing excellent record-keeping skills

Experience with protein purification using AKTA FPLC system is preferred

Experience with aseptic technique and mammalian cell culture is preferred

Learn and perform protein purification using various chromatography techniques and run conjugation reactions

BS/MS and academic or industrial experience with protein purification and characterization. Candidates with a PhD may also be considered.

Experience in protein purification using ion exchange, size exclusion, affinity chromatography and other methods. Experience with FPLC systems, especially AKTA.

Background in protein science, biochemistry, bioanalytical chemistry, enzymology, or chemical biology.

Familiarity with modern analytical techniques and instrumentation for the analysis of proteins (e.g. UV/Vis, HPLC, SDS-PAGE, SEC).

Demonstrated hands-on problem solving, attention to detail, and critical thinking.

Prior experience binding adsorbents into structured forms/materials, such as integration of adsorbents into polymers, membranes, films, fibers, pellets, or extrudates

Minimum of 3 years of research experience post the PhD degree

Experience in synthesis and analysis of MOF and COF materials

Analyze and optimize the heat-transfer properties of different binder systems to achieve optimum MOF/COF system scale performance

Evaluate MOF/COF coatings and structured material stability to various process conditions (temperatures, flow rates, mechanical vibrations)

Quantify adsorption capacity and rates of MOF/COF coatings and structured materials as compared to pristine MOF/COF materials

Flexible work models, including remote work arrangements, where possible

Master’s degree with 4 years of experience in pharma/biopharma or

Bachelor’s degree with 6 years of experience in pharma/biopharm

Leverage in vitro cellular assay tools to establish in vitro-in vivo correlations (IVIVCs) of early-stage multi-specific therapeutic proteins and engineered monotherapies

Design biological and/or biophysical experiments in support of both drug discovery and early development programs, and operating within a modality-independent framework.

Emphasize technology development that can be enabling of in vitro PKDM assessments

Track record of challenging oneself to enhance scientific skills and knowledge

Experience working in a cross collaborative team including bioinformaticians and project managers

Ph.D. in biology or a related discipline with relevant research experience

Experience with chromosomal rearrangements and translocation analysis

Excellent organizational skills and both oral and written communication skills

Ability to think strategically, manage time and workflow, and work independently as well as in a results-oriented research team

Broad knowledge and application of business concepts, procedures and practices. Will perform this job in a quality system environment.

Has broad knowledge of various technical alternatives and their potential impact on the business

Career development with an international company where you can grow the career you dream of .

Free medical coverage for employees* via the Health Investment Plan (HIP) PPO

An excellent retirement savings plan with high employer contribution

Develop the scientific podium and publication strategy in close collaboration with cross-functional teams, and lead the execution of the publication strategy

Record and manage multiple data sets in electronic notebooks, internal data base and excel files

0-3 years of lab experience

Experience with protein purification is preferred (for example, AKTA system operation).

Experience with analytical assays is preferred, such as HPLC and UV-vis

Provide hands-on support for purification development

Execute routine purification development operations from harvest to UF/DF operations following established batch records and SOPs

Design and generate phage display libraries for de novo discovery and affinity maturation (previous phage display experience not required)

Prior experience with protein design including antibody and Fc-fusion proteins as well as plasmid systems for transient and stable mammalian expression

Technical experience in the development and execution of ELISAs, BLI, and other methods for protein quantification and binding characterization

Experience with transient transfection and CHO/HEK293 suspension cell culture is desired

Goal oriented, organized, strong multi-tasking skills

Responsible for leading molecular biology design and construction of complex and multi-domain protein therapeutics including plasmid sequencing, characterization, and scale-up