Scientist, Computational Biology Jobs

The Company

Verve Therapeutics is a biotechnology company created with a singular focus: to protect the world from heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, the company aims to develop transformative, once-and-done therapies for coronary heart disease. Verve’s gene editing medicines are designed to safely edit the genome of adults and mimic naturally occurring gene variants to permanently lower LDL cholesterol and triglyceride levels. The company is advancing a pipeline of precision genetic medicines, led by VERVE-101, which is being developed initially for heterozygous familial hypercholesterolemia, a potentially fatal genetic heart disease. In 2022, Verve was selected as a Top Places to Work by The Boston Globe. Verve is headquartered in Boston, Massachusetts.

The Position

Verve is seeking a highly motivated and talented Scientist with experience in development and application of computational tools for the analysis of next generation sequencing (NGS) data to join our Computational Biology team. This position will focus on implementation and application of high throughput computational analysis pipelines to support the development of gene-editing therapeutics. The ideal candidate will have expertise in design, integration, and troubleshooting of novel and existing bioinformatics methods for NGS data analysis in high performance cloud computing environment and will be responsible for delivering key analyses packages for development programs at Verve. If you are passionate about having an impact on improving the lives of patients with cardiovascular disease by means of cutting-edge gene-editing platforms as part of highly collaborative, fast-paced, multidisciplinary dynamic team, we would love to hear from you!

Job Responsibilities

• Contribution of data visualization and technical writing to scientific reports, manuscripts and regulatory filings supporting development programs at Verve
• Design and benchmarking of novel analysis pipelines for newly established assays and increasing reliability and throughput of existing systems
• Collaboration with cross-functional teams contributing to experiment design, prioritizing program objectives and presenting analysis results to key stakeholders
• Execution of bioinformatics and statistical analysis of high volume NGS data
• Implementation and maintenance of production-scale pipelines for the analysis of diverse sequencing data

Qualifications

• Strong analytical and problem-solving abilities, excellent communication and interpersonal skills
• Working knowledge of applying statistical modeling to draw robust conclusions from complex datasets
• Fluency in tools, frameworks, and methodologies instrumental for reproducible research
• Strong programming skills (Python/R preferred) combined with proficiency in software engineering best practices (version control, documentation, deployment, unit/integration testing) (required)
• Extensive experience with high-performance scalable data-intensive distributed/cloud computing environments utilizing scientific workflow management systems ensuring data integrity and consistency
• Ph.D. or equivalent (with 0-2 years of experience, industrial preferred) in computational biology, bioinformatics, computer science or related discipline (or MS with 4+ years of experience)
• Solid expertise in using common approaches for the analysis of high-volume NGS data (required)

EEO Statement

Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Recruitment & Staffing Agencies

Verve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.