Associate Research Scientist Jobs

Description

• This individual contributor role will collaborate across groups to plan, execute and analyze preclinical mouse studies.
• Provide technical and scientific in vivo pharmacology expertise to advance a variety of drug discovery programs from target identification/validation to IND enabling activities and ultimately to clinical Proof of Concept in patients.
• A wide range of animal models including syngeneic, GEM, CDX, PDX and humanized tumor models are used.
• Develop novel animal models that more closely mimic human cancer to answer mechanistic questions, discover and validate therapeutic targets, and screen/profile drug candidates.
• Conduct in vivo studies to evaluate targets, combination strategies, biomarkers and establish efficacy, PK/PD relationships.
• Characterize and develop small and large molecule therapeutics in close collaboration with your colleagues within in vivo pharmacology and partner lines (discovery biology, medicinal chemistry, MAP/DMPK, preclinical safety, translational research, and early clinical development) as an integral member of drug discovery teams.
• Compliance with IACUC and AALAC regulations.
• Interpretation, documentation and presentation of experiments within a multidisciplinary team environment.

Qualifications

• Advanced in vivo cancer models include syngeneic, genetically engineered mouse (GEM) and humanized tumor models.
• Strong technical skills, a background in characterizing the tumor microenvironment and possess excellent communication skills with a strong commitment to scientific objectivity and excellence.
• The qualified candidate is a highly motivated, interactive, and team-oriented individual that possesses the ability to work in a multi-functional team environment.

Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.

Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Technical Certification Bonus:

• Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.