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Principal Research Scientist Jobs in Massachusetts

Principal Research Associate, Process Development
By Moderna At Norwood, MA, United States
Excellent technical writing skills (lab notebook entries, reports, etc)
Experience with HPLC (SEC, RP, HIC), UV, pH, light scattering, cIEF, DNA sequencing, qPCR, etc
Family care benefits, including subsidized back-up care options and on-demand tutoring
Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
Perform analytical testing (chromatographic, biophysical, molecular biology techniques etc), data analysis and trending
Principal Scientist, Chemoproteomics Jobs
By Matchpoint Therapeutics At Boston, MA, United States
Qualifications/ Education Requirements / Competencies
6 years' experience in nano-scale proteomics methodology employing Thermo Fisher Orbitrap mass spectrometers with additional skill sets required.
Key Responsibilities / Essential Functions
Implement Tandem Mass Tag (TMT)-based quantitative proteomics to elucidate precise interaction between small molecules and proteins.
Develop data dependent acquisition (DDA) MS methods and targeted proteomics-based methods.
Design and execute experiments profiling Post Translational Modifications in intact cells, tissue or cell-culture lysates.
Principal Research Associate, Antibody Lead Optimization
By BioSpace At Waltham, MA, United States
You are skilled in standard molecular biology techniques e.g. PCR, primer design, Gibson cloning etc.
You are skilled in bio-display techniques for antibody discovery and engineering (e.g. phage, yeast or mammalian display)
You have experience or understanding of the generation and analysis of NGS and other high-content biological datasets
Generous personal and family medical, dental and vision benefits with 90% of premiums and deductibles covered
Annual stipend for continuing education with commitment to your career through individualized professional development plan
Support: Carry out antibody optimization campaigns to support Alloy’s ecosystem of partners
Senior Scientist/Principal Scientist, Immunology Drug Discovery
By Jnana Therapeutics At Boston, MA, United States
Leverage drug discovery experience to impact Jnana's Immunology pipeline and strategy.
Experience and success leading drug discovery programs in the biotechnology/pharmaceutical industry, ideally with an auto-immune focused target.
Lead the biological efforts on established drug discovery projects
Represent Biology team in multi-disciplinary project teams to provide robust scientific and technical support; presentation at senior leadership meetings (internal/external).
Build screening funnels to identify emerging chemical matter, and contribute to the overall research and data communication strategy for key programs.
Interrogate novel biology to drive target identification and strategic prioritization of programs.
Research Principal Scientist Jobs
By BioSpace At Boston, MA, United States
Frequent contact with internal and external personnel at various management levels
Broad knowledge in molecular biology, cell biology and immunology, especially in immuno-oncology cell therapy field required.
Experience with CAR-T, CAR-NK or other CAR-based immune effector cell therapies required.
Direct experience in CAR/CCR construction design, optimization and functional validation required.
Experience with CB-NK and/or γδT cells preferred but not required.
Excellent written and verbal communication skills, detail-oriented organization skills, and team collaboration skills required.
Principal Scientist, Pharmacometrics Jobs
By Moderna At Cambridge, MA, United States
Strengthen our pharmacometric capabilities on a continuous basis by evaluating and incorporating new M&S tools and initiating trainings as appropriate
PhD with a focus in pharmacokinetics, pharmacology, pharmaceutics or other related field with 6+ years of drug development experience
Deep and broad experience in clinical and non-clinical drug development with in-depth expertise in quantitative clinical pharmacology and translational medicine
Requires effective skills directed toward driving teamwork, accomplishing results, influencing, and resolving problems across internal and external project teams
Excellent interpersonal, verbal and written communication skills and the ability to function in a highly matrixed team environment are essential.
Family care benefits, including subsidized back-up care options and on-demand tutoring
Principal Scientist, Respiratory Delivery, Drug Product Development
By Moderna At Cambridge, MA, United States
Experience in project management approach to advance complex and fast-paced projects through matrixed (internal and external) teams
Perform required risk assessments, implement appropriate mitigation strategies, and document approaches through appropriate risk management systems
Manage external vendors to evaluate device technologies
Minimum of 8 years (PhD), 10 years (MS), 14 years (BS) industry experience in pulmonary and/or nasal drug delivery
Strong written and oral communication skills
Family care benefits, including subsidized back-up care options and on-demand tutoring
Principal Research Scientist Jobs
By Northeastern University At Boston, MA, United States

About The Opportunity Provides scientific and technical leadership in the management, design, and conducting of the entire research program within the WIoT Institute. Responsibilities include ...

Research Scientist (Robotics & Sensors Team)
By SLB At Cambridge, MA, United States
Excellent problem-solving, organizational, and communication skills.
Develop solutions for Bayesian state estimation, uncertainty quantification, path planning and robotics control
Lead the adoption of AI based algorithms that improve robustness and scalability
Analyze big data sets to assess and correct performance deficiencies
Validate and assess algorithm performance on real and synthetic data
M.S. or Ph.D. degree in Engineering, AI, Applied Mathematics, Robotics, Statistics, or related fields.
Research Scientist (T, Treg, Nk, And Macrophage)
By JURA Bio, Inc. At Boston, MA, United States
Master's Degree (with work experience) or PhD
Strong experience working with T/Treg/natural killer (NK)/macrophage cells, including the ability to isolate and culture cells.
Strong analytical and problem-solving skills, including the ability to interpret and analyze data.
Ability to work effectively in a team, as well as independently.
Proficiency in computer programs and databases commonly used in scientific research.
Ability to work in a laboratory setting and follow established safety protocols.
Scientist, Cancer Vaccines Research
By Moderna At Cambridge, MA, United States
Ph.D. in a biological science or M.S. with extensive relevant experience
Experience/expertise in multiple of the following:
Family care benefits, including subsidized back-up care options and on-demand tutoring
Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
Help identify and prioritize new target antigens and vaccine concepts to advance into discovery and through preclinical development

Are you a passionate and experienced research scientist looking to make a difference? We are looking for a Principal Research Scientist to join our team and lead the development of innovative solutions to complex problems. You will have the opportunity to work with cutting-edge technologies and collaborate with a diverse team of experts. If you are looking for a challenging and rewarding career, this is the perfect opportunity for you!

Overview A Principal Research Scientist is a highly experienced and knowledgeable scientist who is responsible for leading research projects and initiatives. They are responsible for developing and executing research plans, overseeing the research team, and ensuring the accuracy and quality of the research results. Detailed Job Description Principal Research Scientists are responsible for leading research projects and initiatives. They develop and execute research plans, oversee the research team, and ensure the accuracy and quality of the research results. They are also responsible for developing and maintaining relationships with external partners, such as universities, research institutes, and industry partners. They must be able to effectively communicate research results to stakeholders and the public. Principal Research Scientist Job Skills
• Strong analytical and problem-solving skills
• Excellent communication and interpersonal skills
• Ability to work independently and as part of a team
• Ability to manage multiple projects simultaneously
• Knowledge of research methods and techniques
• Knowledge of relevant software and technology
• Ability to interpret and analyze data
Principal Research Scientist Job Qualifications
• Bachelor’s degree in a relevant field, such as biology, chemistry, physics, or engineering
• Master’s degree or PhD in a relevant field
• At least 5 years of experience in a research role
• Experience in leading research projects
• Knowledge of relevant software and technology
• Ability to interpret and analyze data
Principal Research Scientist Job Knowledge
• Knowledge of research methods and techniques
• Knowledge of relevant software and technology
• Knowledge of relevant regulations and standards
• Knowledge of relevant industry trends
Principal Research Scientist Job Experience
• At least 5 years of experience in a research role
• Experience in leading research projects
• Experience in developing and executing research plans
• Experience in managing research teams
• Experience in interpreting and analyzing data
Principal Research Scientist Job Responsibilities
• Develop and execute research plans
• Oversee the research team
• Ensure the accuracy and quality of the research results
• Develop and maintain relationships with external partners
• Communicate research results to stakeholders and the public
• Monitor and evaluate research progress
• Develop and implement new research initiatives