Research Associate 2, Next Generation Sequencing

JOB DESCRIPTION:

• Perform standard molecular biology techniques including DNA & RNA extractions, qPCR and ddPCR analyses, restrictions enzyme digestions and gel electrophoresis.

• Work closely with the Sequencing Core team and internal collaborators to develop and implement the state-of-the-art NGS-based assays and generate high quality NGS sequencing data.

• Maintain detailed electronic laboratory notebook to record day-to-day activities, including experiments, NGS datasets/databases and sample- and reagent-inventories.

• Effectively communicate and collaborate with Sequencing Core team members and with internal and external stakeholders in meetings and through written communications.

• Assume project responsibilities and present project updates, experimental plans, timelines, and results in both small and large group meetings.

• Prepare protocols, SOPs, reports, and other documents to support nonclinical and clinical programs and associated regulatory submissions. This includes assay validation protocols, reagent qualification reports, and data reports.

• Document meticulously all experimental procedures for reproducible and high-quality results.

• Assume responsibility for lab and instrument maintenance.

• Excellent interpersonal, written, and verbal communication skills.
• Experience working in a gene therapy area, especially AAV-based, is a strong plus.
• Open and willing to learn new skills and techniques as needed.
• Ability to work in a fast-paced environment and collaborate in cross-functional teams.

EXPERIENCE:

• At least 2 years of direct wet lab experience with NGS library preparation protocols and preliminary data analysis.

• Familiarity with basic bioinformatics tools for NGS data analysis and data quality check in high performance computing environment or Linux. Proficiency in Microsoft Office suite.

• Hands-on experience with molecular biology methods such as nucleic acid extraction, reverse transcription, PCR, and qPCR/ddPCR analyses.

PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated.

In the U.S., the salary range for this position is $ 76,000 to $ 114,000 per year, which factors in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. A discretionary bonus and/or long-term incentive units may be provided as part of the compensation package, in addition to the full range of medical, financial, and/or other benefits, dependent on the level and position offered.