Senior Scientist, Sequencing Assays

• Design, execute, and interpret data from sophisticated experiments and clearly communicate key findings to colleagues within Resilience R&D
• Attend and present scientific data to colleagues at internal and external meetings
• Contribute to the delivery of project goals by participating in Agile activities, including scrum team meetings, ideation, and cross-functional interactive sessions
• Drive innovation through technical development of novel sequencing-based platforms and analytics, including whole genome sequencing (WGS), whole exome sequencing (WES), epigenome, transcriptome, single-cell RNA and DNA sequencing (scRNA, scDNA)
• Contribute to experimental plans and technical roadmaps to develop and mature both existing and new assay platforms and techniques
• Identify and advise on novel bioinformatic methods and machine learning approaches to extract meaningful insights from complex data analyses

• Mastery and consistent practice of good laboratory techniques and scientific experimental design
• Significant experience with essential molecular biology concepts and methods such as PCR, purification, gel electrophoresis
• Significant experience creating figures, data visualizations, written protocols and/or presentations that clearly distill complex scientific information and roadmaps for a broad audience.
• Demonstrated track record of independent scientific problem solving using systematic, data-driven experimental design and execution
• Significant previous experience in genomics, transcriptomics, and/or proteomics, including secondary analysis pipelines
• Significant previous experience in life sciences development in an industry context
• Subject matter expertise in NGS and/or single cell sequencing assay design and execution, including sample and library preparation for complex sequencing programs enabling high-throughput, data-driven laboratory operations
• Demonstrated experience collaborating with colleagues and partners across a range of technical backgrounds and levels of expertise

• Experience with current and next-generation genome engineering and sequencing technologies, including high dimensional, multimodal and/or multiomic cell characterization methods
• Experience with current and next-generation automation systems, bioinformatics, and/or machine learning as related to biology
• Experience in interfacing with laboratory automation (e.g., automated liquid handlers) and data analysis software
• Experience with novel genome editing nucleases and editing characterization methods (e.g. off-target analyses)
• Experience designing, performing, and/or analyzing data from cell therapy QC assays (incoming patient QC, inline viability, potency and release assays)
• PhD in molecular biology, cell biology, or a related field
• Familiarity with systems used in biomanufacturing and Good Manufacturing Practice (GMP) methodologies
• Direct experience with pre-clinical R&D and IND filing for a cell or gene therapy product or technology

• Intellectually curious with an open, inquisitive mind regarding the future of medicine and biomanufacturing
• Embodies the Resilience phenotypes of grit, rigor, service, EQ+IQ, builder mentality, velocity, and ownership
• Highly organized, self-motivated, and enthusiastic about taking a hands-on approach to collaborative scientific discovery efforts in a fast-paced environment

Resilience offers employees a robust total rewards program including equity, an annual cash bonus program, a 401(k) plan with a generous company match and our benefits package which is thoughtfully designed to support our employees with great healthcare (including medical, dental and vision), family building benefits, life and disability insurance, flexible time off, paid holidays, other paid leaves of absence, tuition reimbursement and support for caregiving needs. Our target annualized base pay hiring range for this position is $135,000.00 - $168,750.00. Actual base pay is dependent upon a number of factors, including but not limited to, the candidate’s geographical location, relevant experience, qualifications, skills and knowledge. Excited about Resilience and the biomanufacturing revolution? We encourage you to apply and start a conversation with one of our recruiters.