Assistant/Associate Project Scientist - Drug Delivery - Dept Of Bioengineering

Position overview
Salary range: The UC academic salary scales set the minimum pay determined by step at appointment. See the following table(s) for the current salary scale(s) for this position: https://www.ucop.edu/academic-personnel-programs/_files/2022-23/july-2022-salary-scales/t38-b.pdf . A reasonable estimate for this position is $86,600-$120,500 annually.
Percent time: 100%
Anticipated start: Fall 2023
Position duration: 24 months. The appointment may be renewable depending on availability of funding and satisfactory performance.
Application Window
Open date: May 12, 2023
Next review date: Thursday, May 25, 2023 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Monday, Jun 12, 2023 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position description
The Department of Bioengineering at the University of California, Berkeley under the supervision of Professor Niren Murthy is seeking an Assistant/Associate Project Scientist to develop and improve Lipid nanoparticle(LNP) based system for drug, DNA, RNA, or gene editing system delivery.
We are looking for a highly motivated individual to join our Lipid Nanoparticles (LNPs) discovery program focused on the utero, cardiovascular, and neuro fields. The successful candidate will be adept at using a range of strategies to design and modify lipids, including peptide- and antibody-based modification, as well as surface charge modification of LNPs. The aim of the project is to develop new LNPs with superior targeting specificities - such as organ specificity, tissue specificity, and cell type specificity - for drug/mRNA/gene-editing system (CRISPR-based) delivery.
The candidate will be responsible for rapidly preparing and screening LNPs formulations, both in vitro and in vivo, using reporter mRNA systems. They will also develop animal models to evaluate the LNPs' delivery efficiency, gene editing (CRISPR-based) efficiency, and potential toxicity.
The candidate will also provide training to undergraduate/graduate/and postdoc candidates and assist the principal investigator in grant writing, preparing manuscripts, and presenting results at various conferences.
Labor Contract : https://ucnet.universityofcalifornia.edu/labor/bargaining-units/ra/contract.html
Qualifications
Basic qualifications (required at time of application)
Ph.D. or equivalent international degree
Preferred qualifications
Ph.D. or equivalent international degree in molecular biology, cell biology, bioengineering, bio-medical engineering, biochemistry
Track record of peer reviewed publications in same or similar to this area.
At least 4 years of postdoctoral experience in the similar discipline.
Experience in the drug/mRNA/ gene editing tool delivery field. Including, delivery vehicle design, formulation development, formulation preparation, formulation screening(in vitro and in vivo), and formulation evaluation.
Lipid nanoparticle-based work experience is strongly desired.
Experience in mammalian gene editing systems- in virto and in vivo, such as CRISPR-based gene editing systems, and Zinc-finger based gene editing systems.
Experience in gene editing efficiency analysis and data analysis, such as Next-generation-sequencing sample preparation.
Experience in animal work: animal handling, animal disease model generation, animal sample analysis(tissue/organ collection, histochemistry sample prepare and staining
Extended knowledge about molecular biology and cell biology
Expertise in molecular techniques including PCR, qPCR, sub-cloning
Experience in protein engineering: plasmid build, protein expression and purification
Cell biology techniques: cell handling, deep sequencing, and FACS
Excellent verbal and written communication skills
Demonstrated ability for internal and external collaborations.
Application Requirements
Document requirements
Curriculum Vitae - Your most recently updated C.V.
Statement of Research
Reference requirements
3 required (contact information only) Apply link: https://aprecruit.berkeley.edu/JPF03934
Help contact: [email protected]
Campus Information
Diversity, equity, inclusion, and belonging are core values at UC Berkeley. Our excellence can only be fully realized by faculty, students, and academic and non-academic staff who share our commitment to these values. Successful candidates for our academic positions will demonstrate evidence of a commitment to advancing equity, inclusion, and belonging.
The University of California, Berkeley is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy see: http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct
In searches when letters of reference are required all letters will be treated as confidential per University of California policy and California state law. Please refer potential referees, including when letters are provided via a third party (i.e., dossier service or career center), to the UC Berkeley statement of confidentiality prior to submitting their letter.
As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs - With Updated Interim Amendments . All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2 , Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being Up-To-Date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment . (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
Positions that are represented by a collective bargaining unit or agent have particular contracts. For more information, please refer to the relevant contract: Lecturer (IX) contract , Postdoctoral (PX) contract , Academic Researcher (RA) contract , and Librarian (LX ) contract . Questions about represented positions can be directed to the hiring unit.
Job location
Berkeley, California
To apply, visit https://aprecruit.berkeley.edu/JPF03934
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