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Staff Optical Engineer Jobs

Company

Nautilus Bio
Address , San Carlos, Ca
Employment type FULL_TIME
Salary $148,500 - $181,583 a year
Expires 2023-06-10
Posted at 1 year ago
Job Description
At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing deep, hard science with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.

We are looking for an Optical Engineer to join our growing Instrument Engineering team. This is an exciting role that will collaborate with a cross-functional team of scientists and engineers to develop and commercialize the world’s first single molecule protein analysis instrument. This individual will be the subject matter expert in the area of optics.

Responsibilities

  • Develop alignment methods, related tools, and processes.
  • Collaborates with the image processing team on development of the full imaging sub-system, including defining the optics specifications and image quality metrics.
  • Drives system and subsystem development to meet requirements on an ambitious schedule, through all phases of commercialization.
  • Assemble, align, test, and integrate optical subsystem into protein decode instrument
  • Provides documentation and training for the transfer of design, assembly, alignment, and troubleshooting to Manufacturing and Service.
  • Designs, executes, analyzes, and documents experiments to evaluate optical characteristics (e.g., image quality (MTF), resolution, focus, signal intensity, and uniformity) to understand how they may be affected by other factors (e.g., alignment tolerances, temperature, scan speed, laser power, vibration, etc…).
  • Works with suppliers to define, specify, select, and qualify tools and test fixtures needed for optical alignment and qualification.
  • Develop detailed characterization plans and study performance of various units; ensure unit to unit matching of system performance.
  • Collaborates with scientists, fluidics engineers, and others in testing the assay to understand how chemistry, molecular biology, fluidics, and hardware interact with and affect optics.
  • Identifies, tracks, and isolates root cause of issues and implements permanent corrective actions.
  • Develops imaging automation scripting, in collaboration with the Instrument Control Software Team, to integrate imaging into the instrument workflow.

Requirements

  • Experience collaborating with optical and opto-mechanical engineers to characterize and develop designs.
  • Experience with optical system assembly methods and materials.
  • Works independently, self-driven, and skilled at effective, proactive communication.
  • 6+ years of relevant experience with the above responsibilities.
  • Experience transferring products and processes to manufacturing.
  • Bachelor’s Degree in optical engineering, mechanical engineering, electrical engineering, bioengineering, physics, or equivalent.

Preferred Skills

  • Familiarity with tools and techniques used to evaluate optical systems’ characteristics, including resolution, distortion, and field curvature.
  • Experience with programming/scripting in Python and LabView.
  • Experienced in development and successful commercialization of products employing rapid, high-resolution fluorescence microscopy of large areas.
  • Familiarity with optical design software such as Code V, LightTools, or Zemax.
  • Familiarity UL or ETL safety and CE standards as pertains to optical systems, particularly laser safety.
  • Proficient with SolidWorks or equivalent 3D CAD software.
  • Analytical expertise using statistical tools/modeling.
  • Experience working with molecular biology, fluidics, and mechatronics.

Nautilus Team Culture

  • We are detail oriented: we do great science by working smart & with diligence where we learn from our trials and mistakes.
  • We are curious go-getters: this is a team of life-long learners who aren’t afraid to tackle the big challenges and we embrace the journey.
  • We are easy to work with: we want our workplace to be one where everyone can share their perspective and be treated with respect and kindness.
$148,500 - $181,582.50 a year
The hiring pay range for this position is based on skills, education and experience relevant to the role; title may be assessed one level lower or higher, accordingly. Other components of total compensation include a competitive options grant at the time of hire (with potential for additional grants).
Benefits include medical, vision, and dental insurance, group and supplemental life insurance, 401k retirement plan, responsible (unlimited) paid time off, parental leave, and more.