Senior Director Program Management

Senior Director, Program Management

Q32 BIO is an exciting clinical stage biotechnology company that has developed an integrated portfolio of therapies to modulate the innate and adaptive immune responses. Our team’s mission is to bring safer, more efficacious therapeutics to patients suffering from a wide range of devastating autoimmune and inflammatory diseases, starting with those rooted in the complement system and interleukin-7 (IL-7) signaling pathways. In pursuit of our bold vision, Q32 Bio has assembled leaders in the field of immunology uniquely positioned to develop novel biologics based on the body’s innate and adaptive immune systems. Our lead molecules include therapeutic fusion proteins that deliver negative regulators of complement activation directly to disease-affected tissues and a monoclonal antibody antagonist of the interleukin-7 receptor (IL-7R).

As we advance our novel therapeutics to treat autoimmune and inflammatory disorders, our dynamic, industry-experienced team continues to grow and we have a current need in support of our multiple Phase 1 and Phase 2 programs as we progress through clinical development. We are looking for a Senior Director, Program Management that will lead our programs through all stages of candidate selection, clinical development and preparation for eventual commercialization. This core and integral team member will lead our Program Team, and providing ongoing guidance to sub-teams, to ensure strategies are successfully developed and executed, leading to optimized asset positioning, timelines and budgets.

RESPONSIBILITIES:

Program Leadership

• Leads cross-functional Program Team, coordinating closely with key sub-teams, to define and meet strategic and tactical program goals, establishing milestones and metrics for tracking; drives and clear, aligned and informed decisions
• Provides overall strategic and operational leadership for key development projects within the Q32 portfolio: working with key stakeholders, drives development and execution of overall program strategy and objectives
• Coordinates efforts between Q32 and external development partners as necessary for the effective support of partnered programs; includes program representation for development partners / alliances as necessary
• Facilitates overall program communications, and represents the program to Senior Leadership Team and key sub-team meetings. Is expected to exercise judgment within defined procedures and policies to determine appropriate action and escalation of issues

Program Planning and Operations

• Identifies all critical path activities and interdependencies between activities. Proactively works with the Program Team and Functional leads to ensure timely action to address any deviation (or potential risk) that could affect meeting defined program objectives. Ensures contingency plans across the development plan and timely action against development issues. Regularly assesses challenge points and opportunities for acceleration
• Provides important operational deliverables, e.g., Program Team agendas & meeting minutes, Program Timelines, Program budget summaries (in close coordination with Finance), Program Goals tracking, and risk mitigation planning
• Partners with Finance to build and maintain an integrated program budget (inclusive of external expenses and internal resource requirements) based on the development assumptions and timeline. Ensures guidance is given to enable Program Team and Functional Leads to estimate and monitor resource requirements (external expenses, FTEs, etc.) for the program to meet its deliverables. Supports the tracking of actuals to budget and communication of deviations to budget or prospectively identified proposed variations

QUALIFICATIONS AND EXPERIENCE:

• Strong skillset regarding program management techniques and methods, familiarity with user-friendly technology for monitoring and reporting progress of R&D programs. Project management certification preferred
• Highly adaptable, ability to work in fast-paced environment, while handling confidential information and issues effectively
• 7-10+ years of industry experience managing clinical programs at a pharmaceutical or biotechnology company. Track record of drug development experience, ideally with experience in protein biologics: knowledge of interconnectivity of the core functional areas of biotech R&D and the overall drug development process, including CMC, regulatory, non-clinical development, and clinical development. Experience managing a clinical development program and team through clinical trials is strongly preferred
• Outstanding leadership and organizational skills, with demonstrated ability to prioritize workstreams/allocate resources and work independently and on teams: skilled at effectively consolidating and communicating information from diverse sources across all functional areas and through all levels of the organization, up to executive management
• BA/BS in a related field required; advanced degree highly preferred
• Exceptional written, oral, interpersonal, and communication/presentation skills and the ability to effectively interface with colleagues throughout the organization at various stages of seniority and experience, including management team
• A flexible, collaborative, and proactive approach as a team leader who can positively and productively impact both strategic and tactical development initiatives