Scientist, Virology Upstream Process Development

Scientist -Virology Upstream Process Development

Position Summary:

Catalent hires people with a passion to make a difference. Your expertise, coupled with our advanced technologies and collaboration with innovative pharmaceutical, biotech, and healthcare companies, will help bring life-enhancing products to the people you know and love. Your talents, ideas, and passion are essential to our mission; to develop, manufacture, and supply products that help people live better healthier lives.

This is a full- time, salaried, position: Monday – Friday, 8:00 am – 5:00 pm.

The Virology Scientist – Upstream Process Development performs independently and productively as an Upstream Development Scientist and actively engages in process and product development within a dynamic project team. The Virology Scientist – Upstream Process Development displays strong technical knowledge, initiative, and scientific commitment and makes significant scientific and technical contributions within the Process Development Group.

The Role:

• Develops and executes large-scale productions and harvest protocols. Utilizes technical knowledge to scale up to manufacturing scales.
• Interacts and collaborates with clients regarding the Upstream activities of the program, including the design and execution of the experiments, analysis, and presentation of the experimental results.
• Leads client projects starting from the development and optimization toward cGMP manufacturing for clinical trials, registration, or improvements of existing processes and products.
• Assists MS&T in preparing the documents for transferring the production processes from PD to cGMP manufacturing. Provide technical support in engineering and GMPs runs.
• Expands the technical capabilities of the Process Development group by offering expertise in areas such as technology development, platform, or systems development, or using a literature precedent.
• Acts as subject matter expert in Upstream Process Development of biologics including, but not limited to vaccines, viral vectors, and recombinant proteins.
• Other duties as assigned.
• Designs and executes the experiments to develop and improve scalable virus and protein production processes utilizing different expression systems focusing on mammalian and insect cell cultures.

The Candidate:

• Upstream process development experience specific to protein/VLP/viral vector production (AAV, lentivirus) and understanding of protein biochemistry (protein folding, protein degradation, aggregation, etc.) and experience in optimization of protein expression.
• General analytical methods applicable for proteins (SDS PAGE electrophoresis, western immunoblotting, plaque assay, etc.).
• Experience working with HSV, lenti- and retroviruses, and/or adenoviruses including primary recovery of viruses from production cultures and with harvest systems – centrifugation, filtration (depth, sterile, tangential flow).
• The ability to work in a team-oriented environment is essential, as this person will work closely with MS&T and Operations and should be able to lead a group of associate scientists to complete the projects successfully.
• Production of material at different scales using various platforms from flasks to stirred tanks and packed bed bioreactors.
• Ph.D. – 0-3 years; MS – 3-6 years; BS - 6-9 years
• Uphold the EHS requirements of this position.
• Degree field in Chemical Engineering, Biochemical Engineering, Chemistry, or Life Science field
• Virus production methods and approaches including isolation, propagation, expansion, and optimization of virus infection kinetics.

Catalent Benefits:

• Generous 401K match and Paid Time Off accrual
• Medical, dental and vision benefits effective day one of employment
• Tuition Reimbursement
• Community engagement and green initiatives
• 152 hours of paid time off annually + 8 paid holidays
• Competitive salary with yearly bonus potential
• Defined career path and annual performance review and feedback process
• Potential for career growth on an expanding team within an organization dedicated to preserving and bettering lives
• Diverse, inclusive culture

Catalent offers rewarding opportunities to further your career! Join the global drug development and delivery leader and help us bring over 7,000 life-saving and life-enhancing products to patients around the world. Catalent is an exciting and growing international company where employees work directly with pharma, biopharma and consumer health companies of all sizes to advance new medicines from early development to clinical trials and to the market. Catalent produces more than 70 billion doses per year, and each one will be used by someone who is counting on us. Join us in making a difference.

Catalent is committed to the health and safety of its employees, visitors and the customers and patients we serve. As a result of the global pandemic, we have modified many of our recruitment and on-boarding processes to maintain everyone’s safety. The Human Resources teams will communicate all necessary safety processes and procedures throughout each stage.

personal initiative. dynamic pace. meaningful work.

Visit Catalent Careers to explore career opportunities.

Catalent is an Equal Opportunity Employer, including disability and veterans.

If you require reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email, and confirming your request for an accommodation and include the job number, title and location to [email protected]. This option is reserved for individuals who require accommodation due to a disability. Information received will be processed by a U.S. Catalent employee and then routed to a local recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process.

Notice to Agency and Search Firm Representatives: Catalent Pharma Solutions (Catalent) is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Catalent employee by a third party agency and/or search firm without a valid written & signed search agreement, will become the sole property of Catalent. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral. Thank you.

Important Security Notice to U.S. Job Seekers:

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