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Scientist, Pharmacometrics Jobs
Company | Moderna |
Address | Cambridge, MA, United States |
Employment type | FULL_TIME |
Salary | |
Category | Biotechnology Research |
Expires | 2023-05-26 |
Posted at | 1 year ago |
The Role:
The Scientist in Pharmacometrics will support pharmacometrics lead in transforming non-clinical and clinical data into analyses that build the basis for model informed development of innovative drugs accessible to patients. The Scientist will actively participate in developing models to quantify and predict exposure-response relationships to inform optimal decision making on key development questions such as dose selection and trial design. The ideal candidate is curious and adaptable to changing priorities.
Here’s What You’ll Do:
About Moderna
In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.
Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com.
Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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The Scientist in Pharmacometrics will support pharmacometrics lead in transforming non-clinical and clinical data into analyses that build the basis for model informed development of innovative drugs accessible to patients. The Scientist will actively participate in developing models to quantify and predict exposure-response relationships to inform optimal decision making on key development questions such as dose selection and trial design. The ideal candidate is curious and adaptable to changing priorities.
Here’s What You’ll Do:
- Provide support to analysis and reporting of population PK and PK/PD analyses
- Continued expanding scientific awareness and presence in quantitative pharmacology and pharmacometrics science, preparation of abstracts and manuscripts for publication
- Apply model-based analyses including non-compartmental analyses, population PK/PD and disease-progression modeling
- Validation and qualification of M&S to support candidate drug development
- Attentive to developing novel approaches and methodologies based on review of relevant scientific literature
- Support in review of M&S sections for regulatory interactions and responses
- Actively contribute to a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative
- Candidate will be curious in exploring new paths for model informed drug development.
- Effective written and verbal communication skills
- Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes
- Sufficient knowledge in pharmacometrics principles and PKPD modeling
- PhD or PharmD with a focus in pharmacokinetics, pharmacology, pharmaceutics or other related field and at least 1 year of industrial drug development experience or 3+ years of academic experience in the field of pharmacometrics
- Hands-on proficiency in using pharmacometrics tools including but not limited to NONMEM, Monolix, R and ADAPT-5 and/or non-linear mixed effect modeling tools
- Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
- Location-specific perks and extras!
- Vacation, sick time and holidays
- Dedicated care coordination support for our LGBTQ+ community
- Discretionary winter shut down
- Exclusive preferred pricing on Peloton fitness equipment
- 401k match and Financial Planning tools
- Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
- Generous paid time off, including:
- Free parking or subsidized commuter passes
- Flexible Spending Accounts for medical expenses and dependent care expenses
- Free premium access to fitness, nutrition, and mindfulness classes
- Family care benefits, including subsidized back-up care options and on-demand tutoring
- Highly competitive and inclusive medical, dental and vision coverage options
- Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
- Adoption and family-planning benefits
- Paid sabbatical after 5 years; every 3 years thereafter
- Complimentary concierge service including home services research, travel booking, and entertainment requests
- Volunteer time to participate within your community
About Moderna
In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.
Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com.
Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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