Research Assistant Jobs

533602
Medical Center
Neurology
Full Time
Opening on: May 22 2023
Technical Grade 5
Add to favorites
Favorited
View favorites
Job Type: Support Staff - Union
Bargaining Unit: SSA
Regular/Temporary: Regular
End Date if Temporary:
Hours Per Week: 35.00
Salary Range: $56,410.11-$56,410.11
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.
Position Summary
We are seeking a Senior Technician to join the laboratory of Dr. Neil Shneider in the Motor Neuron Center at Columbia University Irving Medical Center in New York, NY. The Senior Technician will join an ongoing research effort using novel mouse models of ALS/FTD and human tissue samples to explore molecular and cellular mechanisms underlying neurodegeneration in ALS, frontotemporal dementia (FTD) and related disorders.
Responsibilities
The Senior Technician will:
Carry out basic histological preparations of human and mouse tissues using existing protocols or developing and optimizing additional immunohistochemical methods as necessary
Analyze stained tissues using advanced imaging techniques, including confocal microscopy
Perform molecular biology and biochemical experiments, such as western blotting, electrophoresis, RNA/DNA/Protein isolations, and PCR
Develop and maintain IACUC protocols while also managing the laboratory’s mouse colony through husbandry, genotyping and a range of molecular, cellular and behavioral assays to be characterize different mouse lines
Maintain laboratory equipment and records, perform quality control and quality assurance activities as needed.
Perform miscellaneous functions required to maintain smooth operation of the laboratory such as liaising with the university EH&S office, ensuring the lab is compliant with state, local and university rules and regulations and ordering reagents for lab work.
Minimum Qualifications
Requires a bachelor's degree in chemistry, biology, physics, or related science or equal combination of education, training, and experience.
Minimum 1.5 years working in a professional team environment
A working knowledge of experimental methods in cellular and molecular neurobiology.
Comfort around human-derived tissues/samples.
Preferred Qualifications
Experience in RNA sequencing and computational methods is an advantage but not required.
Prior experience working with mouse models of disease is preferred.
Demonstrated organizational skills and a strong attention to detail
Proficiency in Excel and use of Internet resources for literature searches and database mining.
Comfort working independently or with other team members as required
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.