Lead Scientist/Director, Upstream Process Development, Expat In South Korea

This is a stellar opportunity responsible for leading upstream mammalian cell culture process development and tech transfer activities for the generation of monoclonal antibodies, Antibody Drug Conjugates, Bispecific Antibodies and Fusion Proteins. This is a once-in-a-lifetime Global Expat leadership opportunity within the World’s Largest biologics CMO expanding to 720,000L total mammalian cell culture manufacturing capacity with commercial monoclonal antibody, mRNA vaccine and ADC manufacturing capabilities. You will be charged with overseeing the following activities:

* Leading the development and implementation of upstream cell culture processes from bench scale, scale-up, pilot scale, technology transfer through to clinical manufacturing.

* Providing technical leadership for developing, optimizing, scaling-up, and validating steps in upstream process development for the generation of complex monoclonal antibodies, ADC’s, Bispecific Antibodies and Fusion Proteins.

* Serving as the technical project lead for the development of robust high performing upstream processes with emphasis on transferability to cGMP manufacturing.

* Overseeing cell culture-specific project plans, including raw materials and equipment availability, in preparation for laboratory and pilot scale runs.

* Serving as technical lead for client development projects, communicating project updates and providing technical explanations and rationalization.

* Serving as technical project lead driving the development and implementation of processes from bench to scale-up, including technology transfer through clinical GMP manufacturing.

* Working collaboratively with internal staff to generate project and cost proposals, timelines, and work plans by applying scientific knowledge and business expertise.

Preferred Candidate Background and Expertise:

* 8+ years of Biotechnology industry experience leading upstream mammalian cell culture process development.

* MS or Ph.D. in Chemical Engineering, Biochemistry, Molecular Biology, Biology or related Life Sciences field.

* Upstream mammalian cell culture process development experience for the generation of complex monoclonal antibodies including ADC’s, Bispecific Antibodies or Fusion Proteins.

* Strong Scientific and Engineering technical experience performing upstream cell culture manufacturing activities involving vial thaw, inoculum, media development, media optimization, cell line development, and stainless steel bioreactor operations for the manufacturing of recombinant proteins, monoclonal antibodies, ADCs or mRNA vaccines.

* Subject matter expert in process development areas including high throughput technologies, Ambr bioreactors, technology transfer, scale-up of processes to pilot and manufacturing scales.

* Experience leading cross-functional, multi-national teams including tech transfer teams.

* Excellent understanding and working knowledge of cGMP and biopharmaceutical product development lifecycles and regulatory filings (BLA, MAA, IND).

* Ability to build and maintain strong, positive relationships with customers.

Expatriate Benefits Package:

* Competitive base salary, target bonus, retirement allowance and excellent medical benefits.

* Company paid luxury apartment in Songdo.

* International school tuition paid for children at the top rate Chadwick International School in Songdo, 3 miles from SBL - www.chadwickinternational.org There are also excellent English speaking preschools.

* Company paid airfares to visit the US (or country of origin).

* 3 weeks of vacation time.

* Opportunity to rapidly advance your career within the World's Largest Biologics CMO. A majority of Expats we have placed are now working in their 4th, 5th, 6th and even 10th years. Many have been promoted along the way up to Sr. Director and VP levels

* Work alongside a friendly team of over 100 US Expats and live within the amazing Songdo international community. Other Songdo community employers include the United Nations Green Climate Fund, Celltrion, Merck and Incheon Global Campus with University of Utah, SUNY Stony Brook and George Mason University.

* Opportunity to live and work in the ultramodern New Songdo city with excellent restaurants and an abundance of shopping. Just 20 minutes away from the Incheon ICN International Airport.