Director/Senior Director, Tech Ops

Syros is committed to developing new standards of care for the frontline treatment of patients with hematologic malignancies. Driven by the motivation to help patients with blood disorders that have largely eluded other targeted approaches, Syros is focused on advancing a late-stage clinical pipeline, including tamibarotene, an oral selective RARα agonist in patients with higher-risk myelodysplastic syndrome and acute myeloid leukemia with RARA gene overexpression, and SY-2101, a novel oral form of arsenic trioxide in patients with acute promyelocytic leukemia. For more information, visit www.syros.com and follow us on Twitter (@SyrosPharma) and LinkedIn.

Reporting to the Vice President of Chemical and Pharmaceutical Development, Syros Pharmaceuticals is seeking a Director/Senior Director of Tech Ops to join its team.

Responsibilities

• Responsible for all business and technical oversight of commercial manufacturing at Contract Manufacturing Organizations (CMOs)
• Effectively represent commercial manufacturing at internal and external meetings
• Partner with commercial, legal, finance and global supply chain for commercial forecasting, budgeting, and planning for all manufacturing deliverables
• Collaborate with technical leads in validation, tech transfer, and scale up activities for drug substance and drug product
• Coordinate with analytical quality control, GMP quality assurance and CMC regulatory to ensure compliance and regulatory submissions of commercial products

Success Factors

• Self-motivated; able to work both independently and on a cross-functional team to problem solve
• Excellent attention to detail and problem-solving skills
• Excellent oral and written communication skills for effectively interfacing with vendors and internal stakeholders
• Possesses a sense of urgency and an ability to anticipate and respond quickly to emerging information
• Fosters strong relationships and values collaboration to develop and execute on plans
• Willingness to learn while actively contributing to drug development
• Ability to manage multiple tasks and competing priorities in a fast-paced environment
• Acts with integrity and respect always
• Seeks to build trust
• Entrepreneurial and passionate; enjoys working in a fast-paced, small-company environment

Minimum Qualifications

• Experience with cGMP commercial manufacturing is desired
• Equal consideration given for PhD in chemical engineering or equivalent with a minimum of 10 years of experience in the pharmaceutical or biotechnology industry or at CMOs), or a master’s/bachelor’s degree in chemical engineering or equivalent with a minimum of 14 years of experience.
• Experience working with external CDMO/CRO partners, including support of tech transfer activities

Finally, the candidate will need to embrace our values:

As one team, strengthened by our diversity, we:

• Inspire excellence in all
• Embrace big challenges
• Value each day of patients’ lives
• Communicate transparently
• Operate with integrity and respect

EEO Statement.

Syros Pharmaceuticals Inc. is an Equal Opportunity employer. All Syros recruiting is conducted in a fair and non-discriminatory manner without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Raise Diversity. Elevate Equity. Amplify Inclusion.

The Syros Diversity, Equity, and Inclusion (DEI) Committee invites you to envision your next role in a community where each and every one is empowered to be their best authentic self. Operating with compassion, humility, advocacy, kindness, respect, and awareness, the DEI committee meets regularly to uphold our commitment to an inclusive and welcoming workplace. We believe the unique talents, backgrounds and perspectives of each Syrosian strengthens our coordinated expression, making our company stronger and helping us to achieve our mission of developing medicines to transform patients’ lives.

We are not currently seeking third party assistance with this position.