Protein Scientist Ii Jobs

Generate, manage, evaluate, and maintain critical data in a highly organized manner, providing statistical analysis and troubleshooting where appropriate.

PhD in Molecular Biology or another related discipline with 2-5 years of relevant experience

Extensive experience using molecular biology techniques, such as PCR, dPCR and TIDE

Proficiency in cell & tissue culture (cell lines; experience with hepatocyte culture is a plus), transfection,

Experience with protein extraction, and western blots

Knowledge of CRISPR/Cas9 Gene Editing

Work with multidisciplinary teams and program managers to achieve project milestones on time.

Experiences in high throughput screening and selection-based directed evolution for protein and guide RNA engineering in bacterial and/or mammalian cells.

Experience in early discovery in a CRISPR-based gene and cell therapy company is highly preferred.

Strong oral and written communication skills

Ongoing professional development, including manager training

Access to LinkedIn Learning, a self-guided online education platform

Wellness, caregiver and ergonomics, mental health and education benefits

1+ years of hands-on experience designing and analyzing CRISPR gene editing or epigenetic editing experiments in mammalian cells

1+ years hands-on experience in three of the following areas:

1+ years experience developing novel CRISPR tools for gene and epigenetic editing

1+ years experience developing novel assays in human cells for high throughput tool evaluation

1+ years experience working with disease-relevant human cell lines and primary cells

Excellent verbal, presentation and written communication skills are essential and capacity to effectively work in a team environment

Experience working with internal and external teams in a collaborative environment to deliver on goals and deadlines

Outstanding problem-solving and data analysis skill and ability to independently record scientific progress and maintain detailed laboratory notebook

Previous industry experience in Biotech or Pharmaceuticals

Experience reviewing the proper operation and maintenance of current laboratory equipment and analytical instruments

M.S. with minimum of 2-4 years or B.S./B.A. with 3-5 years Biotech or Pharmaceuticals industry experience preferred

Masters with 1 year of experience or a BS with 3 or greater years of experience.

Hands-on experience running either a Biocore 8K or Carterra LSA.

Strong communication skills in a team environment and an ability to quickly learn and embrace new technologies

Experience with computational methods and machine learning applied to antibody/protein design and optimization

Experience of leading/co-leading and/or managing research projects

Track-record of development of new or improved high throughput protein expression processes.

Effectively analyze and interpret data, as well as communicate updates to management and cross-functional teams

Minimum of 4+ years of research experience, 0-2 years of related experience post-PhD

Proven expertise in protein purification techniques, with working knowledge of FPLC platforms (AKTA, Bio-Rad).

Experience with prokaryotic and eukaryotic expression vectors and construct design for structural biology studies.

Attention to detail, accurate record keeping, and strong oral and written communication skills

Prior experience with protein purification and protein characterization of membrane-spanning proteins such as GPCRs, is a bonus.

10+ years of relevant biotechnology or pharmaceutical industry experience in protein engineering, biochemistry, and structural biology.

5+ years of experience building, leading, and managing protein science teams to successfully meet objectives.

In depth knowledge of the enzymology CRISPR gene editing systems is essential.

Direct experience with state-of-the-art directed evolution methods in both bacterial and mammalian systems is required.

Knowledge of modern structural biology approaches including cryo-electron microscopy and X-ray crystallography.

Excellent collaboration, communication, and interpersonal skills.

Work on a multidisciplinary team using knowledge and experience in protein engineering to advance therapeutic programs.

Hands-on experience in conducting directed evolution campaigns.

Experience with molecular biology (PCR, cloning, library generation), specifically library generation

Experience with high throughput screening and selection methods such as FACS and/or display technologies

Research experience with genome editing technologies, nucleases, and/or DNA modified or DNA binding proteins is strongly preferred

Relevant technical skills for data analysis, DNA and protein sequence analysis, ELN documentation, and presenting results

Strong project management/organization and leadership skills

Technical understanding on product formulation, industrial processes and manufacturing practices, preferred knowledge and experience working on dairy and/or fermented products.

Independently manage medium complexity projects according to stage gate needs. Indirectly mentor Junior product developers and colleagues

Excellent verbal and written communication skills

Proficient in product development systems and general computer skills

Analyze statistical and technical data while identifying trends that translates to the development of the product and the specification.

2+ years of data scientist experience

3+ years of data querying languages (e.g. SQL), scripting languages (e.g. Python) or statistical/mathematical software (e.g. R, SAS, Matlab, etc.) experience

3+ years of machine learning/statistical modeling data analysis tools and techniques, and parameters that affect their performance experience

Experience applying theoretical models in an applied environment

3+ years of experience in a stakeholder or customer-facing analyst or scientist role, and experience with business partnership

Experience in Python, Perl, or another scripting language

BS in a relevant scientific discipline with 3+ years of experience

Experience and proficiency with affinity, size exclusion chromatography and ion exchange chromatography

Prior experience purifying recombinant antibodies using Protein A chromatography is preferred

Prior experience with Cytiva AKTA preparative chromatography platforms and Agilent HPLC systems is preferred

Commuter benefit (ORCA Passport), parking

Purify protein drug candidates and related reagents to support multiple ongoing therapeutic programs

Literature review and investigation to identify key requirements on structure-based computational design for specific GPCR binding antibodies.

Great communication skills, (oral and written), along with a proven record of presentations and publications.

Experienced in research of GPCRs family would be highly desirable.

Hands-on experience in wet-lab techniques, coupled with a willingness to undertake training for additional wet-lab support tasks.

Experienced in molecular dynamics, simulation, physics-based computations or similar. (In particular of Rosetta).

Exceptional collaborative skills are a crucial, as the role requires working closely with a multi-functional team.

Drive excellence in product management.

Strong technical foundation and technical curiosity. Knowledge of biscuit formulation/processes is a strong plus.

Demonstrated ability to handle multiple projects, prioritize and manage complexity, from bench top to full commercialization.

Excellent written and oral communication skills; able to effectively communicate to all levels within the organization

Develop project objectives and technical approach in response to business initiatives.

Analyze results of experiments and translate them into actionable recommendations.

You have experience with protein expression and purification methodologies in mammalian cells

It is a plus if you have demonstrated experience with automation enabled high-throughput production and characterization methods

You pay attention to details and you practice rigorous scientific thinking & clear communication skills

Generous personal and family medical, dental and vision benefits with 90% of premiums and deductibles covered

Annual stipend for continuing education with commitment to your career through individualized professional development plan

You have a willingness to learn and innovate in a dynamic team first environment

Experience, Education and Specialized Knowledge and Skills

Maintain knowledge of state-of-the-art principles and theories and apply this knowledge to the design, execution, and interpretation of experiments.

Expert in ion channel physiology who possesses knowledge and familiarity with high throughput ion channel screening platforms.

Experience using a range of data informatics tools.

Experience interacting with external vendors and with outsourced R&D models.

Possess a strong attention to detail, be highly organized, and have exceptional interpersonal, organizational and communication skills.

2-4 years of experience developing theory and applications to solve challenging real-life data science problems.

Experience with designing computational methods and tools.

Prior knowledge of neuroscience and/or neurodegenerateive disease biology is preferred, but not required.

Excellent oral and written English communication skills.

Develop, implement, and apply computational tools on genomic datasets.

Work closely with biologists to interpret and understand the data.

Minimum Qualifications – Education And Experience

Preferred Qualifications – Education And Experience

Maintain laboratory equipment and manage supplies

Other projects or responsibilities as may be required

Biotech industry experience or research experience

Good analytical and communication skill

You have experience with protein expression and purification methodologies in mammalian cells

It is a plus if you have demonstrated experience with automation enabled high-throughput production and characterization methods

You pay attention to details and you practice rigorous scientific thinking & clear communication skills

Generous personal and family medical, dental and vision benefits with 90% of premiums and deductibles covered

Annual stipend for continuing education with commitment to your career through individualized professional development plan

You have a willingness to learn and innovate in a dynamic team first environment

Chemical synthesis experience in an industrial, academic, or government research lab preferred

Minimum of a summer internship or equivalent research experience in a lab environment

Experience of characterization of chemical compounds via analytical techniques such as NMR, IR, GC, DSC, DMA, TGA, etc.

Knowledge of polymer chemistry and structure property relationships preferred.

Excellent interpersonal skills and ability to work in cross-functional teams.

Strong verbal and written communication skills.

A project manager - You have exceptional project and people management skills

A strong communicator who can easily communicate complex solutions cross functionally and to upper management

Manage cost savings initiatives through our strategic sourcing process to ensure that we hit our targeted budget

Proactively manage quality specifications and factors that influence ingredient standards

Detail-oriented – You possess strong organizational skills and consistently demonstrate a methodical approach to all your work

A team player- You have experience working effectively in teams and prioritize collective goals over personal accolades