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Translational/Preclinical Modeler Jobs
Company | Regeneron |
Address | Tarrytown, NY, United States |
Employment type | FULL_TIME |
Salary | |
Category | Pharmaceutical Manufacturing |
Expires | 2023-09-18 |
Posted at | 10 months ago |
We are looking for a Translational/Preclinical Modeler. The person in this role develops and implements quantitative and mechanistic PK/PD models. We use these models to aid in the understanding of target biology, therapeutic modality selection/optimization. They will also contribute to early clinical trial dose selection and/or design, including human efficacious dose predictions and first-in-human dose selection.
- Remaining informed of emerging science and literature, and effectively collaborates with subject matter experts in Clinical Pharmacology, Quantitative Pharmacology and R&D to advance M&S sciences.
- Effectively integrates and summarizes modeling and simulation (M&S) analyses into useable information for multidisciplinary project teams.
- Providing expert support to pre-clinical PK/PD project representatives and R&D project teams to design, implement and interpret in vitro and in vivo quantitative pharmacology studies. This includes working with the Research PK group to optimize use of mouse PK data to inform translation to nonhuman primate and human PK.
- Have the demonstrated ability to learn new areas of biological sciences to develop quantitative and mechanistic PK/PD models for emerging therapeutic modalities.
- Effectively work in a fast-paced, highly-matrixed team-based environment and leverages scientific reasoning to influence key collaborators.
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