Scientist, Molecular Profiling Jobs

Background
At Immunai, we’re on a mission to revolutionize the way we treat immune diseases. We believe that by harnessing the power of immunomics and machine learning, we can unlock the key to developing the next generation of immunomodulatory drugs.
Our team, comprised of immunologists, engineers, drug developers, computer scientists, and entrepreneurs, uses cutting-edge technology like single-cell multiomics and functional genomics to map the human immune system like never before. We’re delving deep into its inner workings and uncovering novel insights into immune disease pathology.
With the use of neural networks and transfer learning, we’re sifting through a massive immune database and deciphering the mechanisms of action and resistance of existing drugs. This information is helping us identify and validate new immune targets and target combinations and supports the development of improved therapeutics.
Our ultimate goal is to bring breakthrough medicines to patients as quickly and successfully as possible. With our engineering-first approach, we’re confident we can make it happen. Together, we’re shaping the future of immune disease treatment.
Location - NYC, NY on site
For details - [email protected]
Reports to -
Responsibilities
This position offers an opportunity to work in a highly-collaborative environment with world-leading scientists developing and applying state-of-the art profiling technologies to a diverse set of projects at the intersection of the immune system and disease. The successful candidate will work in a fast-paced team and will interface closely with a multidisciplinary team of immunology, molecular biology, and bioinformatics scientists. Specifically, they will contribute to the Molecular Profiling team performing advanced flow cytometry, spatial and molecular analyses on a diverse set of clinical and experimental samples. The successful candidate will be an excellent team player, agile in thought, energetic, and willing to learn new methods and skills.

• Maintain a complete, accurate, and timely electronic record of all experiments using an informatics management system.
• Operation, calibration and maintenance of flow cytometers, cell sorters and related equipment and associated computational hardware
• Cytometry data acquisition, analysis, and documentation of results.
• Actively participate in cross-functional team meetings and communicate effectively with other members of the lab, computational biology, and software team
• Deliver impactful presentations to other colleagues including senior leadership
• Provide support to augment efforts of teams using a wide range of techniques including, but not limited to flow cytometry, immune cell isolation and processing from human specimens, cell cultures and in vitro model systems, single cell genomics methods, and NGS library preparation

Requirements:

• Familiarity with high throughput lab data management
• 4-6 years of experience in Immunology or Immunology-related field; MS with 2-4 years relevant experience, or recent PhD graduate
• Expertise in acquiring and analyzing multiparametric flow cytometry, ideally using the Cytek Aurora
• Direct experience with cell sorting, ideally using the BD FACSAria II/FACSAria Fusion and/or Beckman CytoFLEX
• Experience with sectioning, staining (immunohistochemistry, fluorescence microscopy, in situ hybridization), imaging and basic image analysis is a distinct advantage
• Experience with the CODEX/Akoya PhenoCycler system would be an advantage
• Experience working with tissue samples, including single cell dissociation.
• Experience with protocols for sample and library preparation for single cell multiomics and familiarity with NGS processes

Desired Personal traits

• You have a growth mindset
• You prioritize “We” over “I”
• You collaborate effectively with people of diverse backgrounds and cultures
• You have superior skills and experience, and constantly strive to be world-class in what you do
• You make decisions that favor the company, not yourself or your team
• You constantly challenge your own assumptions, pushing for continuous improvement
• You want to make an impact on humankind
• You enjoy getting things done - with super high quality
• You are candid, authentic, and transparent

Compensation: This position offers a base salary typically between $90,000 and $115,000. There is an opportunity to consider higher compensation above this range based on business need, candidate experience, and or skills.