Scientist - Protein Engineering

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more careers.bms.com/working-with-us

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents. We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

The Discovery Biotherapeutics group at Bristol Myers Squibb in San Diego is seeking a versatile and self-motivated candidate with background in protein engineering to join our Binder Discovery group. The successful candidate, with experience and thorough understanding of protein structure, will join a team that focuses on creative approaches to discover and develop novel biotherapeutic drugs across a number of modalities and programs in oncology, neuroscience, and immune sciences. The ideal candidate will explore innovative engineering solutions to create novel protein-based therapeutics with next-gen designs in generating proof-of-concept data leading to programs into the discovery pipeline.

Responsibilities will include, but are not limited to, the following

• Protein purification by various chromatographies (Protein A, SEC, IEC, Ni-NTA etc) and characterization using various analytical techniques
• Fluency with generating and applying computational predictions and structural analysis to enable drug discovery projects (e.g. Schrodinger, MOE, and/or Rosetta)
• Data analysis, report writing and presentations in team/departmental meetings
• Protein construct design and production in mammalian cells

Basic Qualifications;

• Bachelor's Degree in structural biology, biochemistry, molecular biology, or related discipline and 5+ years of academic / industry experience
• Or
• PhD in structural biology, biochemistry, molecular biology, or related discipline No experience required
• Or
• Master's Degree in structural biology, biochemistry, molecular biology, or related discipline and 3+ years of academic / industry experience

Preferred Qualifications

• Advanced understanding in protein chemistry and protein structure-function relationship
• Some experience with protein-protein binding assays (Biacore, Octet) desired
• Familiarity in AI/ML, protein structure determination or display technologies is a plus
• Ph.D. in structural biology, biochemistry, molecular biology, or related discipline ; Master’s degree with at least 3 years of post-graduate experience
• Translating predictions and structural information to hands-on designs and protein production, purification, and other protein analytical techniques

The starting compensation for this job is a range from $ 97,000 - $135, 300 plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and the where the job is performed.

Final individual compensation will be decided based on demonstrated experience.

For more on benefits, please visit our https //careers.bms.com/working-with-us.

Eligibility for specific benefits listed on our BMS Careers site may vary based on the job and location.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

COVID-19 Information

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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