Dir-Sr Director Supply Chain And Procurement

Our client is an innovative biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, immunologic diseases (e.g., complement-mediated diseases) and cancers. The company’s lead MASP-2 inhibitor targets the lectin pathway of complement and is the subject of a biologics license application pending before FDA for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy. This lead inhibitor is also in multiple late-stage clinical development programs focused on other complement-mediated disorders, including IgA nephropathy, atypical hemolytic uremic syndrome and COVID-19. The company’s inhibitor of MASP-3, the key activator of the alternative pathway of complement, is in a Phase 1 clinical trial.

Position Summary

This position leads the global supply chain function, including procurement, inventory planning & management, and logistics to ensure a reliable supply of safe, high-quality drug products for the Company. Leads the development, implementation and maintenance of policies, procedures, and control systems to reduce costs, streamline procedures, and ensure regulatory compliance of the global supply chain. In collaboration with the relevant team members, this position is responsible for identifying, selecting, negotiating agreements with, and managing various CMC vendors including, but not limited to, those providing raw materials (APIs, excipients, packaging), packaging, labeling, shipment services, GMP storage of API, Drug Product, and final finished goods. Working with clinical and commercial teams to understand anticipated needs, ensures the availability of drug product in the supply chain, as scheduled, and the maintenance of inventory at acceptable levels.

• Develops and leads a culture of learning, respect, and employee growth; Establishes the department's strategic vision and mentor the CMC operations team towards goal achievement
• Collaborates across the CMC function and with Quality Assurance to plan and implement the execution of cGMP activities in support of both clinical and commercial supply chain
• Directs sourcing and supplying of raw materials, utilities, and outside services, as well as coordinating global commercial and clinical procurement efforts
• Works with colleagues in CMC, QA, commercial, clinical, and regulatory affairs to ensure appropriate selection and oversight of vendors
• Promotes adaptation and flexibility in a rapidly changing environment. Acts as a change leader through team building and influence
• Proactively identifies, monitors, and addresses supply chain risks
• Establishes, implements, and manages procurement processes and procedures; Determines KPI’s for vendors and leads business reviews for key vendors
• This role participates in and leads employees, contractors, and vendors in the procurement, planning, manufacturing, inventory management & logistics of the global supply chain
• Selects, develops, and evaluates employees, contractors, and vendors to ensure the efficient operation of the function
• Leads drug and clinical supply and inventory planning and forecasting for the company – working across functions (CMC, Clinical Operations, Quality Assurance, Regulatory, Sales, and Finance); Works with finance/accounting on matters involving inventory-carrying costs; Reviews and plans requirements for acceptable inventory
• Leads the selection and management of vendors to meet supply chain objectives and comply with inventory policies
• Develops short- and long-term goals for the supply chain efforts in support of regulatory submissions, clinical and commercial efforts, and program-driven milestones

Education, Skills and Knowledge:

• Strong organizational and leadership skills to coordinate evolving supply chain timelines and the ability to develop risk-based approaches for the rapid sourcing of materials and release of products
• Twelve (12) to Fifteen (15) years of relevant experience in supply chain management, including 7 - 10 years in biotech or pharmaceutical supply chain management and a minimum of 5 years in a supply chain leadership capacity (dependent on the level)
• Bachelor’s degree in Business, Logistics Management, Chemistry, or equivalent is required; M.S. in Biology, Chemistry or related field is preferred
• Strong communication and partnership with CMC, supply chain, and regulatory teams. The successful candidate will have a demonstrated track record of technical and strategic leadership

Behavioral Competencies Required:

• Leads by creating a positive environment of open communication and staff development
• Delegates work assignments to staff as appropriate, considering employee strengths and expertise to address associated tasks
• Mentors’ individuals, based on individual needs, to meet current job expectations and career goals

Physical Demands Required:

• Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 20 lbs.
• This position requires working around hazardous materials located within the building
• May encounter prolonged periods of sitting or standing

Compensation and Benefits

Salary Range Director $180,000 – $230,000 per year; Sr Director $215,000 - $285,000 per year

Our client offers a competitive total compensation package. Salaries will be determined based on knowledge, skills, education, and experience relevant to the role. Employees are offered medical, dental, vision and life insurance and a 401k plan with a company match. Employees accrue three weeks of vacation and 80 hours of sick time on an annual basis and receive twelve paid holidays throughout the calendar year. This position is eligible for bonus and stock options.