Director Of Clinical Operations

Company Description:

Sensei Biotherapeutics (Nasdaq: SNSE) is an immuno-oncology company focused on the discovery and development of next-generation therapeutics for cancer patients. Through its TMAb™ (Tumor Microenvironment Activated biologics) platform, Sensei develops conditionally active therapeutics designed to disable immunosuppressive signals or activate immunostimulatory signals selectively in the tumor microenvironment to unleash T cells against tumors. Sensei’s lead investigational candidate is SNS-101, a conditionally active antibody designed to block the V-domain Ig suppressor of T cell activation (VISTA) checkpoint selectively within the low pH tumor microenvironment, where VISTA acts as a suppressor of T cells by binding the receptor PSGL-1. The company is also developing SNS-102, a conditional binding monoclonal antibody targeting V-Set and Immunoglobulin Domain Containing 4 (VSIG-4), as well as SNS-103, also a conditionally active monoclonal antibody targeting ecto-nucleoside triphosphate diphosphohydrolase-1 (ENTPDase1), also known as CD39.

Job Summary:

Sensei Biotherapeutics is seeking a Director of Clinical Operations to oversee and manage our clinical trial programs. The Director of Clinical Operations will be responsible for leading the operational strategy and execution of clinical trials across multiple therapeutic areas. This individual will manage a team of clinical operations professionals and collaborate closely with cross-functional teams including Clinical Development, Regulatory Affairs, Medical Affairs, and Program Management, as well as external vendors supporting Sensei’s clinical operations.

Responsibilities:

• Provide regular updates on clinical trial progress to executive leadership and ensure that all clinical trial documentation is accurate, complete, and submitted on time.
• Develop and implement effective risk management strategies to identify and mitigate potential clinical trial risks.
• Work with vendors and contract research organizations (CROs) to ensure that clinical trial activities are managed efficiently and within budget.
• Develop and execute clinical operations plans for all phases of clinical trials, including protocol development, trial initiation, site selection, study start-up, enrollment, monitoring, data management, and trial close-out.
• Manage and oversee the day-to-day activities of clinical operations staff, ensuring adherence to timelines, budgets, and quality standards.
• Collaborate with cross-functional teams to ensure that clinical trial protocols are in line with regulatory requirements and ethical standards.
• Establish and maintain relationships with clinical trial investigators and site staff, ensuring proper training and oversight to ensure high quality data collection.

Requirements:

• This is an exciting opportunity for an experienced clinical operations professional to join a dynamic, growing biotechnology company and play a critical role in advancing innovative therapies to improve patient lives. We offer a competitive compensation package, comprehensive benefits, and opportunities for professional growth and development.
• Demonstrated experience leading and managing clinical operations teams.
• Experience working with CROs and managing vendor relationships.
• Strong knowledge of clinical trial design, conduct, and management.
• Bachelor’s degree in a scientific discipline, advanced degree preferred.
• Excellent communication, leadership, and project management skills.
• Ability to work independently and collaboratively with cross-functional teams.
• Minimum of 10 years of experience in clinical operations in the biotechnology or pharmaceutical industry.

EEO Statement

Sensei is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.