Bioinformatics Analyst Ii – Translational Research

The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Immunology is to advance the fundamental understanding of human immunology through the study of immune health and diseases where excessive or impaired immune responses drive pathological processes. The Institute will employ a multi-disciplinary team approach in collaboration with academic centers of human immunology to generate novel mechanistic insights into the immune synapse in health and in diseases such as autoimmunity or oncology. The Institute will simultaneously provide a foundational data set and tools for future immunological research as well as a novel collaboration portal for the broader scientific community.

The Allen Institute for Immunology is seeking a Bioinformatics Analyst II – Translational Research with experience in analyzing omics data for biological research to support our joint research projects with industry partners. The ideal candidate is a self-motivated team player who can work closely with internal scientists and external collaborators, an excellent communicator who can translate ideas into solid data analysis plan and testable hypotheses, a quick learner who can adapt new methodologies to achieve goals, and a tireless worker who can complete projects under time constraint.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions

• Analyze data from clinical trials, biomarker research, and/or target identification and prioritization
• Work closely with immunologists and bioinformaticians to explore omics data for hypothesis generation and testing
• Generating high-quality figures and tables for presentations and publication
• Use both standard and tailored methods to analyze clinical metadata and multi-modal omics data, including but not limited to: scRNA-seq, scATAC-seq, CITE-seq, TEA-seq, flow cytometry, and proteomics
• Assist scientists in data analysis and data presentation
• Identify potential biomarkers and/or drug targets for disease of interest and perform network analysis
• Review, implement, troubleshoot, and improve analytic methods developed by others internally or externally
• Meet analysis deadlines and be able to pivot between multiple projects

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education And Experience

• Bachelor's degree in Bioinformatics or closely related discipline
• 2 years of equivalent experience in a biological research or industry setting

Preferred Education And Experience

• Basic knowledge of human immunology
• Ability to learn and implement new software tools and packages
• Able to work independently as well as in a collaborative high paced environment under minimum supervision
• Familiarity with cloud computing and/or linux
• Excellent written and verbal communication skills and organizational skills
• Master's degree in bioinformatics or closely related disciplines
• Demonstrated experience in writing code for omics data analysis
• Fluency in R and/or Python
• Basic knowledge of molecular biology and wet-lab omics technologies
• Hands on experience analyzing high throughput omics data
• Good problem-solving skills, curious and eager to learn new skills
• Experience in generating high quality graphs for presentation and/or publication
• Experience using Git or similar version control system
• Experience in analyzing data from clinical trials, biomarker research, and/or target identification and prioritization
• 2 - 5 years of experience in industry research
• Demonstrated success in a multidisciplinary team environment
• Self-motivated, a team player, attentive to details, and able to handle multiple projects simultaneously

Work Environment

• May enter laboratory environment - possible exposure to chemical, biological, or other hazardous substances.

Physical Demands

• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment

Position Type/Expected Hours of Work

• Occasional evening and weekend hours required
• This role is currently able to work both remotely and onsite in a hybrid work environment. We are a Washington State employer, and the primary work location for all Allen Institute employees is 615 Westlake Ave N.; any remote work must be performed in Washington State.

Travel

• Attendance and participation in national and international conferences may be required

Additional Comments

• **Please note, this opportunity offersrelocation assistance**
• **Please note, this opportunity offers work visa sponsorship**

Annualized Salary Range

• Final salary depends on required education for the role, experience, and level of skills relevant to the role, along with work location, where applicable.
• $80,253 - $112,355 *

Benefits

Employees (and their families) are eligible to enroll in benefits per eligibility rules outline in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401k plan. Paid time off is also available as outlined in the Allen Institutes Benefits Guide. Details on the Allen Institute’s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits .

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.