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Scientist - Downstream Process Development
Company | BioSpace |
Address | New York, NY, United States |
Employment type | FULL_TIME |
Salary | |
Category | Internet News |
Expires | 2023-07-24 |
Posted at | 10 months ago |
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
- Lead technical interactions for the downstream process development, process validation, and technical supports for GMP Manufacturing
- Participate in the expansion of internal process development capabilities
- Lead, design, and perform downstream process development studies, including resin and buffer screens, process characterization, and scale up for novel viral vectors
- Support internal viral vector material generation
- Mentor/manage junior team members
- Build process understanding to support technology transfer to internal or external groups for manufacturing at pilot, engineering, clinical, or commercial scales
- Maintain a robust communication and presentation to all relevant internal functional groups and external partners.
- Author and review documents including development reports, SOPs, tech transfer protocols/reports, CMC sections of regulatory filings
- Utilize electronic lab notebook and management systems (ELN/LIMS) to document and manage experimental data, protocols, reports, equipment status, and inventory
- MSc with 1+ years, or BSc with 3+ years of relevant experience in a scientific discipline such as bioengineering, chemical engineering, biochemistry, or related field
- Experience with regulatory filling, and quality assurance and quality control systems preferred.
- Creative thinking, high level of ownership, multitasking in a fast-paced work environment.
- Experience with AAV gene therapy process development preferred.
- Experience with affinity chromatography and TFF preferred.
- Experience with designing and implementing IEX chromatography process development required.
- Experience in process technical transfer preferred.
- Excellent organizational, documentation, and communication skills; adaptive learning, critical thinking, and the ability to work well in a team
- Experience in timeline management and resource planning preferred.
- Lilly currently anticipates that the base salary for this position could range from between $61,500 to $160,600 and will depend, in part, on the successful candidate’s qualifications for the role, including education and experience. Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Of course, the compensation described above is subject to change and could be higher or lower than the range described above. Further, Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees
- Position Location: NYC, Prevail Therapeutics a wholly owned subsidiary of Eli Lilly.
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