Associate Scientist, Predictive Model Strategic Initiative

Gaithersburg, MD

Do you have bold ambitions and a passion for science? If you do, then come join the dedicated and passionate scientists at AstraZeneca Oncology R&D where we have the bold ambition to eliminate cancer as a cause of death.

About AstraZeneca

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration.

Innovate and Push the Boundaries of Science in Oncology R&D

Join a dedicated Oncology team that’s growing fast and building a strong track record of success. Our pioneering approach is identifying and treating patients earlier, focusing on early-stage cancer trials and listening and evolving based on their needs. As a team we are deeply committed to transforming the lives of patients living with cancer – with the ultimate aim of eliminating cancer as a cause of death. There’s no better place to make an impact – here we are uniquely placed with the funding, the ambition and the bravery to make it happen.

Main Responsibilities

The Clinical Immuno-Oncology (IO) Discovery team within Early Oncology Discovery ICC department in Gaithersburg Maryland is seeking a highly motivated, lab-based Associate Scientist with a background in cancer and/or cancer immunobiology to be a part of the new Strategic Initiative for Predictive Models. The responsibilities of this position include developing and performing human tissue-based assays from cancer patients, to characterize biological mechanisms of action of novel biologics drugs and drug combinations under investigation in clinical trials for the treatment of cancer.

Essential Requirements:

• Bachelor’s Degree with 0-3 years of experience
• Great teammate who is well organized with strong interpersonal skills and excellent oral and written communication skills.
• Experience with developing and testing IO agents and combinations in ex vivo 3D platforms.
• Strong hands-on skills in cellular biology and tumor immunobiology, including processing of patient tumor biopsies, histology, multiplex IHC/IF, multi-color flow cytometry (FACS), ELISA, western blotting, luminescence assays, cell killing assays, high content imaging, and spatial biology profiling.
• Strong cell biology experience in sterile cell culture techniques such as isolation and culture of primary cells in microfluidic devices.
• Ability to make detailed observations, analyze data, and interpret results independently.
• Proven ability to collaborate in matrixed team.
• Preparation of precise technical summaries, protocols, quantitative analyses, and maintenance of appropriate documentation.

Desired Qualifications:

• Experience working with primary tissue samples and ascites from cancer patients; experience in patient-derived organotypic tumor systems.
• Ability to independently design and execute research plans for one or more programs, and to review, analyze, and interpret experimental results

About Our Gaithersburg Oncology Hub

The Gaithersburg site (https://www.youtube.com/watch?v=GOvxXGjBd1w) employs more than 3,500 experts in our field and is only a short drive from Washington, DC. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg campus offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria, game rooms, community garden and much more.

So, What’s Next-

Are you already envisioning yourself joining our team? Good! We can’t wait to hear from you!

If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: August 16, 2023

Competitive Remuneration And Benefits Apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.