Associate Scientist, Analytical Development, Genomics

Pushing the frontier of solid cancer therapy, Neogene Therapeutics is a global, clinical stage biotechnology company built on the premise of innovation and novel paradigm-changing science. Using tumor mutation profiles to engineer fully individualized T cell therapies, Neogene is bringing new hope to address the current limitations of treatments available today.

We offer the opportunity to join a highly dynamic biotech with locations in Amsterdam, Netherlands and in Santa Monica, CA. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies.

Neogene values pro-active team-players who pursue their goals with dedication, endurance, and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide an exciting opportunity for your career.

Position Summary

Neogene is seeking an experienced Associate Scientist, Analytical Development, Genomics who will focus on the development of molecular biological assays for characterizing engineered TCR T-cell therapy. Additionally, this role contributes to the establishment, development, and qualification of PCR and NGS assays. This role is based out of Santa Monica, CA, and reports directly to the Senior Engineer, Analytical Development.

Responsibilities

• Improve the data management of analytical laboratories, ex. automation, digitalization, and data visualization.
• Develop molecular biological assays for characterizing T-cell therapy drug substance and drug products using qPCR, dPCR and NGS.
• Complete projects, testing and tasks as assigned and report results by deadlines.
• Perform routine assays for drug product release and characterization.
• Support cross-functional projects with research, process development and manufacturing groups

Requirements

• Hands-on experience in Bioinformatic data analysis.
• Strong written and presentation skills for scientific studies and projects.
• Experience in designing, executing and optimizing assays and analyzing data using multiple molecular biological platforms, e.g. qPCR, dPCR, Illumina Miseq, Oxford Nanopore..etc.
• Hands-on experience in other immunoassays (flow cytometry, ELISA..etc.) is a plus
• Experience working with Python/R in bioinformatics data analysis, SQL data management, and data visualization tools such as Power BI or Tableau.
• Experience in statistical analysis to analyze complex biological datasets.
• Detail-oriented in both technical assay development and data analysis.
• Experience working with lab automation systems, including scripting, operating, and maintenance.
• Enjoy a fast-paced, dynamic start-up company environment and able to adjust workload based upon changing priorities.
• PhD in Molecular Biology, Immunology, Cell Biology, or related scientific discipline OR MS (in aforementioned disciplines) with 3+ years relevant industry experience.
• Hands-on experience in nucleotide extraction, PCR and library preparation.

The anticipated salary range for candidates who will work in Santa Monica, CA is $105,000 to $137,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job type and length of experience within the industry, education, etc.

At Neogene we celebrate the diversity of our employees and our leadership. Neogene is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.

DE&I Statement

Headline: We embrace our individual differences.

Together, We Strive To Uphold a Value System That Promotes

"Our mission is to build a workforce reflective of our communities to be receptive to patients' broad and unique perspectives, enabling us to empathize with their needs.

• Zero tolerance for discrimination
• Opportunities for continuous learning to drive behavioral change and to be respectful of other points of view
• A collaborative culture that leverages the diverse perspectives of employees and supports courage

We are committed to an emotionally and psychologically safe workplace that trusts employees to boldly explore innovative solutions. We recognize that intentionally embracing diversity at Neogene, empowers us to better relate to patients, and advance our mission to deliver cures where none exist.”