Senior Scientist, Cancer Immunology

Senior Scientist, Cancer Immunology

Gaithersburg, MD

We are seeking a highly motivated Senior Scientist who has an extensive scientific expertise in cancer immunology/immunotherapy. A successful candidate will have substantial experience in studying T cells and myeloid cells both in vivo and in vitro, independently design and execute projects/experiments, troubleshoot and optimize methods, as well as generate, interpret and report scientific data clearly and concisely. Candidate should hold PhD in Immunology or related field and have a proven postdoctoral record with strong publications. Strong expertise with mouse tumor models is desirable.

As a Senior Scientist in our Oncology R&D department, you will be a key member of a team focused designing novel therapeutics to target myeloid biology and support projects through drug discovery and development process. You will bring your theoretical and practical expertise in immunology to establish assay systems and deliver datasets that will have direct impact on immune-oncology therapeutics.

This senior scientist will work under the direction of the team leader, Executive Director and Chief Scientist in Cancer Immunology, Dmitry Gabrilovich. List of his publications can be found here https://pubmed.ncbi.nlm.nih.gov/?term=gabrilovich+d&sort=date

Oncology Vision

AstraZeneca’s vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to ultimately eliminate cancer as a cause of death. A broad pipeline of next-generation medicines is focused on bringing novel concepts in immuno-oncology to unmet medical need.

About Our Gaithersburg Oncology Hub

The Gaithersburg site (https://www.youtube.com/watch?v=GOvxXGjBd1w) employs more than 3,500 experts in our field and is only a short drive from Washington, DC. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg campus offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria, game rooms, community garden and much more.

What Does This Role Involve?

• Ensures own work and work of peers is compliant with Good Laboratory Practice, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations
• Maintains a well-developed understanding of approaches to investigate the function of myeloid cells and aspects of drug discovery
• Independently conducts cancer immunology and drug discovery research experiments using techniques in immunology, molecular and cellular biology
• May be asked to lead or co-lead a project team and contribute to scientific publication goals
• Assesses and reports data with little guidance in a clear and concise manner with a strong understanding of its implications within the overall context of drug discovery
• Is an active member of the team liaising between programs/departments and sharing scientific knowledge and feedback on other’s experiments to ensure the efficient relay of information and translation of data

Essential Skills and Capabilities

• Extensive experience in studying T cells or myeloid cells: MDSC, macrophages, dendritic cells
• Excellent organizational and communication skills
• A PhD, or equivalent experience, in immunology and cancer biology
• Strong hands-on skills in basic biochemical and immunological methods including multi-color flow cytometry (FACS), ELISA/multiplex assays, western blotting, luminescence assays, cell killing assays, high content imaging.
• Ability to work in a high paced team environment, plan and meet timelines
• Proven track record of success in your research, and experience preparing written scientific reports (eg, manuscripts) and oral presentations to broad and diverse audiences

Desirable for the role

• Experience developing cancer immunotherapy including cancer vaccines and cellular therapies
• In vivo expertise in murine tumor models

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, groundbreaking cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what’s next-

Are you already envisioning yourself joining our team? Good! We can’t wait to hear from you!

If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: June 2, 2023

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.